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一种快速即时护理荧光成像设备有助于预防改良根治性乳房切除术后的移植物排斥反应。

A Rapid Point-of-care Fluorescence Imaging Device Helps Prevent Graft Rejection Post Modified Radical Mastectomy.

作者信息

Mirza Shahzad, Gupta Aayush

机构信息

Department of Microbiology, Dr. D.Y. Patil Medical College and Hospital and Research Centre, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.

Department of Dermatology, Dr. D.Y. Patil Medical College and Hospital and Research Centre, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.

出版信息

J Glob Infect Dis. 2024 May 24;16(2):76-78. doi: 10.4103/jgid.jgid_148_23. eCollection 2024 Apr-Jun.

DOI:10.4103/jgid.jgid_148_23
PMID:39081504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11286084/
Abstract

Pathogenic bacteria in wounds impede successful skin grafting. However, their detection relies on culture methods, which delay confirmation by several days. Real-time fluorescence imaging detects bacteria, allowing for rapid assessment and documentation. We herein report a post modified radical mastectomy, surgical site infection with multidrug-resistant spp. that underwent repeated antibiotic therapy and debridement and eventually grafting. In this case, a real-time fluorescence imaging device helped prevent graft rejection.

摘要

伤口中的病原菌会阻碍皮肤移植的成功。然而，它们的检测依赖于培养方法，这会使确诊延迟数天。实时荧光成像可检测细菌，从而实现快速评估和记录。我们在此报告一例改良根治性乳房切除术后手术部位感染多重耐药菌的病例，该患者接受了反复的抗生素治疗和清创，最终进行了移植手术。在这个病例中，实时荧光成像设备有助于防止移植排斥反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/616c/11286084/5c9127e43ea1/JGID-16-76-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/616c/11286084/060a2299838e/JGID-16-76-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/616c/11286084/db2c8881c7df/JGID-16-76-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/616c/11286084/5c9127e43ea1/JGID-16-76-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/616c/11286084/060a2299838e/JGID-16-76-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/616c/11286084/db2c8881c7df/JGID-16-76-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/616c/11286084/5c9127e43ea1/JGID-16-76-g003.jpg

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本文引用的文献

1
Utility of a real-time fluorescence imaging device in guiding antibiotic treatment in superficial skin infections.实时荧光成像设备在指导浅表皮肤感染抗生素治疗中的应用
Indian J Dermatol Venereol Leprol. 2022 May-Jun;88(4):509-514. doi: 10.25259/IJDVL_856_19.
2
Routine Fluorescence Imaging to Detect Wound Bacteria Reduces Antibiotic Use and Antimicrobial Dressing Expenditure While Improving Healing Rates: Retrospective Analysis of 229 Foot Ulcers.通过常规荧光成像检测伤口细菌可减少抗生素使用和抗菌敷料支出，同时提高愈合率：对229例足部溃疡的回顾性分析
Diagnostics (Basel). 2020 Nov 10;10(11):927. doi: 10.3390/diagnostics10110927.
3
Use of a bacterial fluorescence imaging system to target wound debridement and accelerate healing: a pilot study.
利用细菌荧光成像系统靶向清创并加速愈合：一项初步研究。
J Wound Care. 2020 Jul 1;29(Sup7):S44-S52. doi: 10.12968/jowc.2020.29.Sup7.S44.
4
Efficacy of a bacterial fluorescence imaging device in an outpatient wound care clinic: a pilot study.一种细菌荧光成像设备在门诊伤口护理诊所的疗效：一项试点研究。
J Wound Care. 2019 Jul 2;28(7):438-443. doi: 10.12968/jowc.2019.28.7.438.
5
Understanding Real-Time Fluorescence Signals from Bacteria and Wound Tissues Observed with the MolecuLight i:X.理解通过MolecuLight i:X观察到的来自细菌和伤口组织的实时荧光信号。
Diagnostics (Basel). 2019 Feb 26;9(1):22. doi: 10.3390/diagnostics9010022.
6
The Impact of Microbial Communities on Wound Healing: A Review.微生物群落对伤口愈合的影响：综述
Ann Plast Surg. 2018 Jul;81(1):113-123. doi: 10.1097/SAP.0000000000001450.
7
Point-of-care fluorescence imaging predicts the presence of pathogenic bacteria in wounds: a clinical study.即时护理荧光成像预测伤口中病原菌的存在：一项临床研究。
J Wound Care. 2017 Aug 2;26(8):452-460. doi: 10.12968/jowc.2017.26.8.452.
8
Success rate of split-thickness skin grafting of chronic venous leg ulcers depends on the presence of Pseudomonas aeruginosa: a retrospective study.慢性静脉性腿部溃疡的断层皮片移植成功率取决于绿脓假单胞菌的存在：一项回顾性研究。
PLoS One. 2011;6(5):e20492. doi: 10.1371/journal.pone.0020492. Epub 2011 May 31.