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腹腔镜胃切除术后切口部位坏疽性脓皮病:一例报告

Postoperative Pyoderma Gangrenosum in a Laparoscopic Gastrectomy Port Site: A Case Report.

作者信息

Yamauchi Suguru, Ando Yuji, Kaji Sanae, Jun Chen, Egawa Hiroki, Yoshimoto Yutaro, Kubota Akira, Yube Yukinori, Orita Hajime, Fukunaga Tetsu

出版信息

Juntendo Iji Zasshi. 2022 Aug 15;68(5):521-525. doi: 10.14789/jmj.JMJ22-0017-CR. eCollection 2022.

Abstract

BACKGROUND

Postoperative pyoderma gangrenosum (PPG) is a rare inflammatory skin disease of unknown etiology characterized by blistering and ulcerative lesions in postoperative wounds. Untreated pyoderma gangrenosum (PG) is potentially life-threatening; therefore, immediate and appropriate treatment is essential. Although PPG and surgical site infection (SSI) present similar clinical findings, they should be differentiated because of their conflicting treatment modalities.

CASE PRESENTATION

An 82-year-old man with comorbidities of pulmonary tuberculosis, chronic obstructive pulmonary disease, and diabetes underwent laparoscopic gastrectomy for gastric cancer. On postoperative day 6, fever exceeding 39°C, port wound redness, and pain was observed. Laboratory tests revealed severe inflammatory reactions: white blood cell, 42,800/μL and C-reactive protein, 30.2 mg/mL. The patient was diagnosed with SSI and treatment with antibiotics and drainage was started; however, his general and wound conditions also worsened. Therefore, he was diagnosed with PG because painful skin findings were exacerbated by external stimuli and no significant bacteria were detected in the culture test. Treatment with oral prednisolone was started, which significantly improved his skin and inflammatory conditions.

CONCLUSION

We managed a rare case of PPG that occurred in a port wound after laparoscopic gastrectomy. If atypical clinical findings of postoperative SSI are observed, general surgeons should recognize and consider PPG as a differential diagnosis.

摘要

背景

术后坏疽性脓皮病(PPG)是一种病因不明的罕见炎症性皮肤病,其特征为术后伤口出现水疱和溃疡性病变。未经治疗的坏疽性脓皮病(PG)可能危及生命;因此,立即进行适当治疗至关重要。尽管PPG和手术部位感染(SSI)有相似的临床表现,但由于它们的治疗方式相互冲突,所以应加以区分。

病例报告

一名82岁男性,患有肺结核、慢性阻塞性肺疾病和糖尿病,因胃癌接受了腹腔镜胃切除术。术后第6天,观察到体温超过39°C、切口周围皮肤发红和疼痛。实验室检查显示严重的炎症反应:白细胞42,800/μL,C反应蛋白30.2mg/mL。该患者被诊断为SSI,并开始使用抗生素和引流进行治疗;然而,他的整体状况和伤口情况也恶化了。因此,由于外部刺激会加剧疼痛的皮肤表现,且培养试验未检测到明显细菌,他被诊断为PG。开始口服泼尼松龙治疗后,他的皮肤和炎症状况有了显著改善。

结论

我们处理了一例腹腔镜胃切除术后切口处发生的罕见PPG病例。如果观察到术后SSI的非典型临床表现,普通外科医生应认识到并将PPG作为鉴别诊断考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1a4/11284291/dc3c8094980a/2188-2126-68-5-0521-g001.jpg

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