Al-Ozairi Ebaa, Mandani Yousef, Alfaleh Ghanima, Raj Jincy, Alshammari Shadan, Le Roux Carel W
Clinical Research and Clinical Trials Unit, Dasman Diabetes Institute, Kuwait, Kuwait.
Ministry of Health, Kuwait, Kuwait.
Front Nutr. 2024 Jul 16;11:1349392. doi: 10.3389/fnut.2024.1349392. eCollection 2024.
Ultra-processed foods are associated with metabolic dysfunction and driving chronic diseases. The Metabolic Matrix is a tool used to reformulate products to promote positive metabolic outcomes. The Kuwait Danish Dairy Company (KDD) has used this tool to develop a no-added-sugar products. This clinical trial tested the glycaemic response of a no-added-sugar ice cream in individuals with type 2 diabetes. The hypothesis was that the no-added-sugar ice cream would have a substantially better postprandial glycemic response than conventional ice cream in patients with type 2 diabetes. In this randomized cross over designed study, postprandial glycemic response was measured after 300 grams of no-added-sugar ice cream or normal ice cream was consumed. Despite similar composition and palatability, the postprandial responses were better with the no-added sugar ice cream, albeit that the natural sugar in the product still resulted in a marked postprandial glycaemic response. This finding emphasizes the necessity of clearly communicating to both patients and healthcare professionals that "no-added-sugar" does not equate to "zero total sugar." The path to improved metabolic health involves not only product improvement but also transparent messaging to enable informed dietary choices. Reformulation resulting in palatable no-added sugar products provides an opportunity for companies to Create Shared Value by addressing the important social problems such as obesity and type 2 diabetes, by creating scalable solutions, that are profitable. ClinicalTrials.gov, identifiers NCT06135935.
超加工食品与代谢功能障碍及引发慢性病有关。代谢矩阵是一种用于重新配方产品以促进积极代谢结果的工具。科威特丹麦乳品公司(KDD)已使用该工具开发了无糖产品。这项临床试验测试了无糖冰淇淋对2型糖尿病患者的血糖反应。假设是无糖冰淇淋在2型糖尿病患者中的餐后血糖反应会比传统冰淇淋显著更好。在这项随机交叉设计研究中,在食用300克无糖冰淇淋或普通冰淇淋后测量餐后血糖反应。尽管成分和适口性相似,但无糖冰淇淋的餐后反应更好,尽管产品中的天然糖仍导致明显的餐后血糖反应。这一发现强调了向患者和医疗保健专业人员明确传达“无糖”并不等同于“总糖为零”的必要性。改善代谢健康的途径不仅包括产品改进,还包括透明的信息传递,以实现明智的饮食选择。重新配方生产出口味良好的无糖产品为公司提供了一个通过创造可扩展的盈利解决方案来解决肥胖和2型糖尿病等重要社会问题从而创造共享价值的机会。ClinicalTrials.gov标识符:NCT06135935。