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罕见部位的子宫外平滑肌瘤:两例病例报告及文献综述

Extrauterine leiomyomas in uncommon locations: two case reports and literature review.

作者信息

Yavuz Onur, Kula Ali Hakan, Bayramoğlu Zeynep, Aydin Nur Yağ Mur, Mankan Kadir Alper, Akdöner Aslı

机构信息

Department of Obstetrics and Gynecology, Dokuz Eylül University School of Medicine, Izmir, Türkiye.

Department of Pathology, Dokuz Eylül University School of Medicine, Izmir, Türkiye.

出版信息

Front Med (Lausanne). 2024 Jul 16;11:1408247. doi: 10.3389/fmed.2024.1408247. eCollection 2024.

DOI:10.3389/fmed.2024.1408247
PMID:39081688
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11286391/
Abstract

OBJECTIVES

This study aims to provide an overview of the diagnosis, treatment, and follow-up management of vulvar and vaginal leiomyomas through the presentation of two rare cases.

METHODS

Detailed clinical presentations, surgical procedures, histopathological examinations, and follow-up outcomes of two cases of vulvar and vaginal leiomyomas are described. Relevant literature is also reviewed to contextualize the findings.

RESULTS

Both patients underwent successful surgical excision of the leiomyomas with no perioperative or postoperative complications. Histopathological examinations confirmed the diagnosis of leiomyoma based on characteristic microscopic features and immunohistochemical analyses.

CONCLUSION

Vulvar and vaginal leiomyomas are rare benign tumors that require careful evaluation for accurate diagnosis and appropriate management. Surgical excision remains the primary treatment modality, and long-term follow-up is essential for monitoring recurrence and ensuring favorable outcomes.

摘要

目的

本研究旨在通过介绍两例罕见病例,概述外阴和阴道平滑肌瘤的诊断、治疗及随访管理。

方法

描述了两例外阴和阴道平滑肌瘤的详细临床表现、手术过程、组织病理学检查及随访结果。还回顾了相关文献以阐明研究结果。

结果

两名患者均成功进行了平滑肌瘤手术切除,无围手术期或术后并发症。组织病理学检查根据特征性显微镜特征和免疫组织化学分析确诊为平滑肌瘤。

结论

外阴和阴道平滑肌瘤是罕见的良性肿瘤,需要仔细评估以进行准确诊断和适当管理。手术切除仍然是主要的治疗方式,长期随访对于监测复发和确保良好预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bfe/11286391/94009fc72f50/fmed-11-1408247-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bfe/11286391/47df91588420/fmed-11-1408247-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bfe/11286391/7949a157a811/fmed-11-1408247-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bfe/11286391/94009fc72f50/fmed-11-1408247-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bfe/11286391/47df91588420/fmed-11-1408247-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bfe/11286391/7949a157a811/fmed-11-1408247-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bfe/11286391/94009fc72f50/fmed-11-1408247-g0003.jpg

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J Midlife Health. 2025 Apr-Jun;16(2):144-147. doi: 10.4103/jmh.jmh_7_25. Epub 2025 Jun 23.
2
Benign Calcified Axillary Leiomyoma in a Young Male: A Case Report.一名年轻男性的良性钙化性腋窝平滑肌瘤:病例报告
Cureus. 2025 May 29;17(5):e85059. doi: 10.7759/cureus.85059. eCollection 2025 May.

本文引用的文献

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Transvaginal excision of vaginal paraurethral leiomyoma: A video case report.经阴道切除阴道旁尿道平滑肌瘤:一例视频病例报告。
Eur J Obstet Gynecol Reprod Biol. 2023 Nov;290:11-13. doi: 10.1016/j.ejogrb.2023.09.008. Epub 2023 Sep 11.
2
A case of misdiagnosed leiomyoma of the vulva: A case report.外阴平滑肌瘤误诊 1 例:病例报告。
Medicine (Baltimore). 2023 Feb 10;102(6):e32868. doi: 10.1097/MD.0000000000032868.
3
Challenges in management of Bartholin gland leiomyoma: A case report.巴氏腺平滑肌瘤管理中的挑战:一例报告
Clin Case Rep. 2023 Jan 28;11(1):e6449. doi: 10.1002/ccr3.6449. eCollection 2023 Jan.
4
Vaginal leiomyoma mimicking a Cystocele (report case).酷似膀胱膨出的阴道平滑肌瘤(病例报告)
Int J Surg Case Rep. 2022 Apr;93:106955. doi: 10.1016/j.ijscr.2022.106955. Epub 2022 Mar 19.
5
Vulvar Leiomyoma Presenting as a Painless Vulvar Mass.表现为无痛性外阴肿物的外阴平滑肌瘤
J Minim Invasive Gynecol. 2022 Feb;29(2):187-189. doi: 10.1016/j.jmig.2021.10.014. Epub 2021 Nov 5.
6
Vulvar myoma: A case report and review of literature.外阴平滑肌瘤:病例报告及文献复习。
Taiwan J Obstet Gynecol. 2021 Sep;60(5):924-926. doi: 10.1016/j.tjog.2021.07.026.
7
Recurrent vaginal epithelioid leiomyosarcoma; a case report from Botswana and review of the literature.复发性阴道上皮样平滑肌肉瘤;来自博茨瓦纳的一例病例报告及文献复习。
Afr J Reprod Health. 2021 Feb;25(1):161-168. doi: 10.29063/ajrh2021/v25i1.17.
8
Vaginal leiomyoma: medical imaging and diagnosis in a resource low tertiary hospital: case report.阴道平滑肌瘤:资源匮乏的三级医院中的医学影像检查与诊断:病例报告
BMC Womens Health. 2020 Jan 21;20(1):12. doi: 10.1186/s12905-020-0883-2.
9
Evaluation of treatments for Bartholin's cyst or abscess: a systematic review.巴氏腺囊肿或脓肿治疗方法的评估:系统评价。
BJOG. 2020 May;127(6):671-678. doi: 10.1111/1471-0528.16079. Epub 2020 Feb 4.
10
Bartholin Duct Cyst and Gland Abscess: Office Management.巴氏腺囊肿和腺体脓肿:门诊处理。
Am Fam Physician. 2019 Jun 15;99(12):760-766.