Jha Tanvi, Ahuja Arvind, Chachra Anuj, Paliwal Purnima, Dutta Kamna
Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Department of Obstetrics and Gynaecology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
J Midlife Health. 2025 Apr-Jun;16(2):144-147. doi: 10.4103/jmh.jmh_7_25. Epub 2025 Jun 23.
Extrauterine leiomyomas (EULs) are rare benign smooth muscle tumors that arise outside the uterus, often leading to diagnostic challenges.
To evaluate the clinical and pathological characteristics of EULs and their management in a tertiary care setting.
This retrospective study reviewed 51 cases of EULs over a 5.5-year period. Data on demographics, clinical presentation, tumor location, histology, and treatment were analyzed.
The mean patient age was 41.6 years, with 41.2% aged 40-50 and 15.7% post-menopausal. Abnormal uterine bleeding (AUB) was the most common symptom (66.7%). Tumors were most frequently located in the cervix (72.5%), followed by the broad ligament (11.8%) and ovaries (7.8%). Histologically, EULs resembled uterine leiomyomas, showing spindle-shaped cells and low mitotic activity. Surgical excision was the primary treatment.
EULs, though uncommon, should be considered in differential diagnoses of pelvic masses. Accurate histopathological evaluation is essential to avoid misdiagnosis and unnecessary intervention. This study enhances current understanding of EUL presentation and management.
子宫外平滑肌瘤（EULs）是罕见的良性平滑肌肿瘤，发生于子宫外，常导致诊断难题。
评估三级医疗机构中子宫外平滑肌瘤的临床和病理特征及其管理方法。
这项回顾性研究在5.5年期间对51例子宫外平滑肌瘤病例进行了回顾。分析了人口统计学、临床表现、肿瘤位置、组织学和治疗的数据。
患者平均年龄为41.6岁，40 - 50岁的患者占41.2%，绝经后患者占15.7%。异常子宫出血（AUB）是最常见的症状（66.7%）。肿瘤最常位于宫颈（72.5%），其次是阔韧带（11.8%）和卵巢（7.8%）。组织学上，子宫外平滑肌瘤类似于子宫平滑肌瘤，表现为梭形细胞和低有丝分裂活性。手术切除是主要治疗方法。
子宫外平滑肌瘤虽不常见，但在盆腔肿块的鉴别诊断中应予以考虑。准确的组织病理学评估对于避免误诊和不必要的干预至关重要。本研究增进了当前对子宫外平滑肌瘤表现和管理的认识。
