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佩吉特样网状细胞增生症(沃林格-科洛普病):组织细胞标志物(溶菌酶)研究及超微结构观察

Pagetoid reticulosis (Woringer-Kolopp disease): histiocyte marker (lysozyme) study and ultrastructural observations.

作者信息

Natarajan S, Wilson P D

出版信息

Dermatologica. 1985;171(5):332-7. doi: 10.1159/000249447.

Abstract

A case of pagetoid reticulosis is presented. Histopathology showed infiltration of the epidermis by mononuclear cells. Twenty percent of the mononuclear cells showed the presence of lysozyme indicating a histiocytic origin. Electron microscopy confirmed the presence of lymphocytes and histiocytes but these cells were outnumbered by Sézary cells. The presence of large numbers of Sézary cells indicates that pagetoid reticulosis is a cutaneous T-cell lymphoma closely related to mycosis fungoides.

摘要

报告1例派杰样网状细胞增生症。组织病理学显示表皮有单核细胞浸润。20%的单核细胞显示有溶菌酶,提示组织细胞来源。电镜证实有淋巴细胞和组织细胞存在,但这些细胞数量少于塞扎里细胞。大量塞扎里细胞的存在表明派杰样网状细胞增生症是一种与蕈样肉芽肿密切相关的皮肤T细胞淋巴瘤。

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Woringer-Kolopp disease (pagetoid reticulosis).沃林格-科洛普病(蕈样网状细胞增生症)
Am J Dermatopathol. 1983 Apr;5(2):153-8. doi: 10.1097/00000372-198304000-00013.
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Pagetoid reticulosis: a disease of histiocytic origin.
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Pagetoid reticulosis. A further case report with a review of the literature.
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