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成人使用草药减肥的特征及影响因素的真实世界证据。

Real-world evidence of characteristics and factors influencing herbal medicine use for weight loss in adults.

作者信息

Lee Boram, Yang Changsop, Yim Mi Hong

机构信息

KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.

Digital Health Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.

出版信息

Front Pharmacol. 2024 Jul 16;15:1437032. doi: 10.3389/fphar.2024.1437032. eCollection 2024.

DOI:10.3389/fphar.2024.1437032
PMID:39081960
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11286466/
Abstract

BACKGROUND

Obesity imposes a significant socioeconomic burden owing to its high prevalence. In response to the adverse outcomes associated with conventional pharmacotherapy and the challenges of low adherence to lifestyle interventions, herbal medicine has surfaced as an actively utilized approach for weight loss. Therefore, this study aimed to analyze the characteristics and influencing factors of herbal medicine users for weight loss in adults.

METHODS

Overall, 22,080 participants were included based on data from the Korea National Health and Nutrition Examination Survey from 2010 to 2019. Simple logistic regression analyses were used to derive the associations between herbal medicine use for weight loss and individual characteristics. Three models were constructed utilizing multiple logistic regression analyses to assess the associations between herbal medicine use for weight loss and the combined characteristics of predisposing, enabling, and need factors according to Andersen's model.

RESULTS

In the full adjustment model, women, younger adults, those with higher incomes, and individuals reporting higher levels of perceived stress were more prone to use herbal medicine for weight loss in the past year. Adults who identified body image as being fat/very fat, those who consumed alcohol, and those classified as severely obese by body mass index were also more prone to use herbal medicine for weight loss. In particular, adults with a higher rate and amount of weight loss in the past year were more likely to use herbal medicine for weight loss compared to those experiencing weight gain/no changes/loss of 0-3 kg.

CONCLUSION

Our study was the first to derive the characteristics and influencing factors of herbal medicine users for weight loss among adults. These findings hold significant promise for informing future research endeavors and policy decision-making for effective resource distribution for obesity treatment.

摘要

背景

肥胖因其高患病率而带来重大的社会经济负担。鉴于传统药物治疗的不良后果以及生活方式干预依从性低的挑战,草药已成为一种积极应用于减肥的方法。因此,本研究旨在分析成人减肥草药使用者的特征及影响因素。

方法

总体而言,基于2010年至2019年韩国国家健康与营养检查调查的数据纳入了22,080名参与者。采用简单逻辑回归分析得出减肥草药使用与个体特征之间的关联。根据安德森模型,利用多元逻辑回归分析构建三个模型,以评估减肥草药使用与易患因素、促成因素和需求因素的综合特征之间的关联。

结果

在完全调整模型中,女性、年轻人、收入较高者以及报告感知压力水平较高的个体在过去一年中更倾向于使用草药减肥。认为自己体型胖/非常胖的成年人、饮酒者以及根据体重指数被归类为重度肥胖的人也更倾向于使用草药减肥。特别是,与体重增加/无变化/减重0 - 3千克的人相比,过去一年中减肥率和减肥量较高的成年人更有可能使用草药减肥。

结论

我们的研究首次得出了成人减肥草药使用者的特征及影响因素。这些发现对于为未来研究工作提供信息以及为肥胖治疗有效资源分配的政策决策具有重要意义。

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