C 反应蛋白在脑胶质瘤患者中的预后价值：一项荟萃分析。
Prognostic value of C-reactive protein in patients with glioma: a meta-analysis.
机构信息
Clinical Laboratory, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, Zhejiang, 313000, China.
出版信息
Biomark Med. 2024;18(13-14):629-637. doi: 10.1080/17520363.2024.2380246. Epub 2024 Jul 31.
Abstract
In this meta-analysis, we investigated C-reactive protein (CRP)'s role in glioma prognosis prediction. We conducted the current meta-analysis in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for systematic reviews and meta-analyses. An analysis of the prognostic effect of CRP on glioma was conducted using combined hazard ratios (HRs) and 95% confidence intervals (CIs). The combined data suggested that a higher CRP level was markedly related to poor overall survival in glioma (hazard ratio: 1.73; 95% CI: 1.22-2.46; = 0.002). According to results in the present meta-analysis, elevated CRP levels were significantly related to inferior overall survival in glioma.
摘要
在这项荟萃分析中，我们研究了 C-反应蛋白（CRP）在胶质瘤预后预测中的作用。我们根据系统评价和荟萃分析的首选报告项目指南进行了当前的荟萃分析。使用合并风险比（HR）和 95%置信区间（CI）分析 CRP 对胶质瘤预后的影响。合并数据表明，CRP 水平较高与胶质瘤的总生存期差明显相关（风险比：1.73；95%CI：1.22-2.46；P=0.002）。根据本荟萃分析的结果，CRP 水平升高与胶质瘤总生存期较差显著相关。
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