Letter to the Editor: Intraoperative microelectrode recording during asleep deep brain stimulation of subthalamic nucleus for Parkinson disease: a case series with systematic review of the literature.

This letter discusses the recent study by Izzo et al., which explored intraoperative microelectrode recording (MER) during asleep deep brain stimulation (DBS) of the subthalamic nucleus for Parkinson's disease. The study's integration of a systematic review positions its findings within the broader context of neurosurgical advances. Highlighting the practicality and patient comfort of the frameless technique under general anesthesia, it emphasizes the significance of MER in optimizing electrode placement, thereby potentially enhancing patient outcomes. The letter suggests future research directions, including randomized clinical trials, to assess the clinical benefits of this methodology further.