Department of Ecology and Evolutionary Biology, University of Michigan, 1105 North University Avenue, Biological Sciences Building, University of Michigan, Ann Arbor, MI 48109, USA.
Museum of Paleontology, University of Michigan, 1105 North University Avenue, Biological Sciences Building, University of Michigan, Ann Arbor, MI 48109, USA.
Sci Adv. 2024 Aug 2;10(31):eadp0114. doi: 10.1126/sciadv.adp0114. Epub 2024 Jul 31.
Complex patterns of genome evolution associated with the end-Cretaceous [Cretaceous-Paleogene (K-Pg)] mass extinction limit our understanding of the early evolutionary history of modern birds. Here, we analyzed patterns of avian molecular evolution and identified distinct macroevolutionary regimes across exons, introns, untranslated regions, and mitochondrial genomes. Bird clades originating near the K-Pg boundary exhibited numerous shifts in the mode of molecular evolution, suggesting a burst of genomic heterogeneity at this point in Earth's history. These inferred shifts in substitution patterns were closely related to evolutionary shifts in developmental mode, adult body mass, and patterns of metabolic scaling. Our results suggest that the end-Cretaceous mass extinction triggered integrated patterns of evolution across avian genomes, physiology, and life history near the dawn of the modern bird radiation.
与白垩纪末期（白垩纪-古近纪）大灭绝相关的基因组演化的复杂模式限制了我们对现代鸟类早期进化历史的理解。在这里，我们分析了鸟类分子演化的模式，并在exon、intron、非翻译区和线粒体基因组中识别出不同的大进化阶段。起源于白垩纪-古近纪边界附近的鸟类谱系表现出分子进化模式的许多转变，这表明在地球历史的这一点上存在基因组异质性的爆发。这些推断的替代模式的转变与发育模式、成年体质量和代谢缩放模式的进化转变密切相关。我们的研究结果表明，白垩纪末期的大灭绝在现代鸟类辐射的黎明时期触发了鸟类基因组、生理学和生活史的综合进化模式。
