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对从伊朗采集的精油进行化学成分、抗病原和抗癌活性的测定。

Determining of chemical composition, anti-pathogenic and anticancer activity of essential oil collected from Iran.

作者信息

Afkar Soheila, Somaghian Shahram Ahmadi

机构信息

Agriculture Department, Payame Noor University, Tehran, Iran.

Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.

出版信息

Nat Prod Res. 2024 Jul 31:1-9. doi: 10.1080/14786419.2024.2381650.

Abstract

In this study, three different ecotypes of collected from Lorestan province, Iran. three habitats including Khorramabad (ecotype 1), Aleshtar (ecotype 2), and Delfan (ecotype 3) counties (ecotype 3) were selected. In addition to analysing the chemical composition of the essential oils, for the first time, the effects of essential oils of these ecotypes against plant pathogenic bacterial including and together with , a biocontrol agent, and viability of colon tumour cell (SW742) was evaluated. Results showed that ecotype 1 had the highest concentration of the essential oil. All three bacteria showed the same level of sensitivity to the essential oils of extracted from three different ecotypes. Considering the findings of the effects of essential oils on SW742 tumour cell viability, we can suggest that essential oil obtained from ecotype 3 can be used to reduce the cell viability of SW742 tumour cells. It can be concluded that essential oil can be used to reduce tumour cell viability and their anti-microbial activity against plant pathogens.

摘要

在本研究中,从伊朗洛雷斯坦省采集了三种不同生态型的[具体植物名称未给出]。选取了包括霍拉马巴德(生态型1)、阿莱什塔尔(生态型2)和德尔凡(生态型3)县在内的三种栖息地(生态型3)。除了分析精油的化学成分外,首次评估了这些生态型的精油对包括[植物病原菌名称未给出]和[植物病原菌名称未给出]以及一种生物防治剂[生物防治剂名称未给出]的植物致病细菌的影响,以及结肠肿瘤细胞(SW742)的活力。结果表明,生态型1的精油浓度最高。所有三种细菌对从三种不同生态型中提取的[植物名称未给出]精油表现出相同程度的敏感性。考虑到精油对SW742肿瘤细胞活力影响的研究结果,我们可以认为从生态型3获得的[植物名称未给出]精油可用于降低SW742肿瘤细胞的活力。可以得出结论,[植物名称未给出]精油可用于降低肿瘤细胞活力及其对植物病原菌的抗菌活性。

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