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对L.不同部位的生物活性成分、营养特性、抗氧化、抗菌和抗溶血潜力的探索

Exploration of Bioactive Components, Nutritional Properties, Antioxidant, Antimicrobial and Antihemolytic Potential of Different Parts of L.

作者信息

Tourabi Meryem, El Abdali Youness, Faiz Khaoula, Mssillou Ibrahim, Agour Abdelkrim, Louasté Bouchra, Merzouki Mohammed, Salamatullah Ahmad Mohammad, Bourhia Mohammed, Younous Youssouf Ali, Metouekel Amira, Lyoussi Badiaa, Derwich Elhoussine

机构信息

Laboratory of Biotechnology, Conservation and Valorisation of Bioresources Faculty of Sciences, Sidi Mohamed ben Abdellah University Fez Morocco.

Laboratory of Biotechnology, Environment, Agri-Food, and Health (LBEAS), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed ben Abdellah University Fez Morocco.

出版信息

Food Sci Nutr. 2025 Jul 27;13(8):e70634. doi: 10.1002/fsn3.70634. eCollection 2025 Aug.

Abstract

is frequently utilized as a natural treatment in conventional medicine to treat diverse illnesses, including gastrointestinal, respiratory, and inflammatory disorders. The present study aimed to unveil the phenolic composition, as well as the antioxidant, antihemolytic, and antimicrobial potential of different parts of . HPLC-DAD analysis was employed to identify the phenolic components of extracts from different plant parts. The total flavonoid and phenolic contents were measured. Four assays were conducted to assess the antioxidant capacity in vitro, including DPPH, ABTS, RP, and TAC assays. The antihemolytic potential of different parts of was also evaluated. The minimum inhibitory concentration (MIC) was determined using the microdilution method, and the minimum bactericidal concentration (MBC) was assessed. Thirteen compounds were identified in extracts, among them kaempferol, quercetin, ferulic acid, and gallic acid. However, the aerial part of (leaves and stem) and root extract contained a high polyphenol content and exhibited nutritional properties. Leaf extract comprises a high level of flavonoid content combined with significant antioxidant potency and demonstrated excellent antibacterial and antifungal activity. Moreover, a significant antihemolytic capacity was observed in the root, stem, and seed extracts. Based on the findings of the current study, extracts exhibited high antihemolytic power along with antioxidant and antimicrobial properties, suggesting their potential use in the development of plant-based drugs in the future.

摘要

在传统医学中,它经常被用作一种天然疗法来治疗各种疾病,包括胃肠道、呼吸道和炎症性疾病。本研究旨在揭示其不同部位的酚类成分以及抗氧化、抗溶血和抗菌潜力。采用高效液相色谱-二极管阵列检测(HPLC-DAD)分析法来鉴定不同植物部位提取物中的酚类成分。测定了总黄酮和酚类含量。进行了四项体外抗氧化能力测定,包括二苯基苦味酰基自由基(DPPH)、2,2'-联氮-双-3-乙基苯并噻唑啉-6-磺酸(ABTS)、还原力(RP)和总抗氧化能力(TAC)测定。还评估了其不同部位的抗溶血潜力。采用微量稀释法测定最低抑菌浓度(MIC),并评估最低杀菌浓度(MBC)。在其提取物中鉴定出13种化合物,其中包括山奈酚、槲皮素、阿魏酸和没食子酸。然而,其地上部分(叶和茎)和根提取物含有较高的多酚含量,并表现出营养特性。叶提取物含有高水平的黄酮类化合物,具有显著的抗氧化能力,并表现出优异的抗菌和抗真菌活性。此外,在根、茎和种子提取物中观察到显著的抗溶血能力。基于本研究的结果,其提取物具有较高的抗溶血能力以及抗氧化和抗菌特性,表明它们在未来植物源药物开发中具有潜在用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/badb/12301569/80f3b03b5a7f/FSN3-13-e70634-g007.jpg

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