心律失常的无创神经调节
Non-invasive Neuromodulation of Arrhythmias.
机构信息
University of Oklahoma Health Sciences Center.
University of Oklahoma Health Sciences Center.
出版信息
Card Electrophysiol Clin. 2024 Sep;16(3):307-314. doi: 10.1016/j.ccep.2023.12.001. Epub 2024 Jan 4.
Abstract
The autonomic nervous system plays a central role in the pathogenesis of arrhythmias. Preclinical and clinical studies have demonstrated the therapeutic effect of neuromodulation at multiple anatomic targets across the neurocardiac axis for the treatment of arrhythmias. In this review, we discuss the rationale and clinical application of noninvasive neuromodulation techniques in treating arrhythmias and explore associated barriers and future directions, including optimization of stimulation parameters and patient selection.
摘要
自主神经系统在心律失常的发病机制中起着核心作用。临床前和临床研究已经证明了在神经心脏轴的多个解剖靶点进行神经调节的治疗效果，可用于心律失常的治疗。在这篇综述中，我们讨论了非侵入性神经调节技术治疗心律失常的原理和临床应用，并探讨了相关的障碍和未来方向，包括刺激参数的优化和患者选择。
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