Department of Wood and Paper Science and Technology, Faculty of Natural Resources, University College of Agriculture & Natural Resources, University of Tehran, Karaj, Iran.
Department of Bio Systems, Faculty of New Technologies and Aerospace Engineering, Zirab Campus, Shahid Beheshti University, Tehran, Iran.
Int J Biol Macromol. 2024 Oct;277(Pt 1):133846. doi: 10.1016/j.ijbiomac.2024.133846. Epub 2024 Jul 31.
This study aimed to enhance the properties of polyvinylpyrrolidone (PVP) for use as biocompatible facial masks. To achieve this, nanofibers were developed by blending PVP with cellulose nanofibers (CNFs) and Aloe vera (AV) powder using electrospinning. The results showed that incorporating CNFs and AV into the PVP matrix led to the formation of smooth and uniform nanofibers. In particular, adding 3-6 wt% AV powder in PVP/CNF composites improved fiber diameter distribution and uniformity compared to pure PVP. The PVP/CNF/AV nanofibers exhibited desirable properties for facial mask applications. They displayed 86-93 % porosity, which allowed for efficient moisture absorption capacity of up to 1829 %, and excellent water vapor permeability rate of 3.92 g/mh. The mechanical properties of the electrospun nanofiber composites were evaluated through tensile testing. The results showed that Young's modulus values decreased progressively with the addition of CNFs and AV powder to the PVP polymer matrix, indicating a plasticizing effect that enhances flexibility. The fracture strain remained similar across all composites, suggesting that CNFs and AV did not significantly weaken the PVP matrix. The tensile strength initially increased with CNF addition but decreased with incremental AV loading. Biocompatibility studies revealed that all nanofibers exhibited excellent fibroblast viability, surpassing 98 %. This indicates that incorporating CNFs and AV did not compromise cell viability, further highlighting the suitability of the PVP/CNF/AV composites for facial mask applications.
本研究旨在改善聚乙烯吡咯烷酮（PVP）的性能，以将其用作生物相容性面膜。为了实现这一目标，通过静电纺丝将 PVP 与纤维素纳米纤维（CNF）和芦荟（AV）粉末混合来开发纳米纤维。结果表明，将 CNF 和 AV 掺入 PVP 基质中导致形成光滑且均匀的纳米纤维。特别是，与纯 PVP 相比，在 PVP/CNF 复合材料中添加 3-6wt%的 AV 粉末改善了纤维直径分布和均匀性。PVP/CNF/AV 纳米纤维具有用于面膜应用的理想性能。它们显示出 86-93%的孔隙率，可实现高达 1829%的有效吸湿能力和 3.92g/mh 的出色水蒸气透过率。通过拉伸测试评估了静电纺纳米纤维复合材料的机械性能。结果表明，随着 CNF 和 AV 粉末添加到 PVP 聚合物基质中，杨氏模量值逐渐降低，表明具有增塑作用，可提高柔韧性。所有复合材料的断裂应变保持相似，表明 CNF 和 AV 并未显著削弱 PVP 基质。拉伸强度最初随 CNF 增加而增加，但随 AV 加载量的增加而降低。生物相容性研究表明，所有纳米纤维均表现出出色的成纤维细胞活力，超过 98%。这表明，掺入 CNF 和 AV 不会影响细胞活力，进一步突出了 PVP/CNF/AV 复合材料在面膜应用中的适用性。
