Toonstra J
J Am Acad Dermatol. 1985 Nov;13(5 Pt 1):799-805.
The case of a male diabetic patient with recurrent bullous lesions restricted to the hands is reported. Areas of spongiosis in the epidermis, as well as subepidermal blister formation, were observed in repeated biopsies. On electron microscopy, separation was seen at the level of the lamina lucida. No immunopathology was observed in involved skin. A review of forty-four reported cases of bullosis diabeticorum is given.
报告了一例男性糖尿病患者，其反复出现的大疱性皮损局限于手部。在重复活检中观察到表皮海绵形成区域以及表皮下疱形成。电子显微镜检查显示在透明层水平出现分离。受累皮肤未观察到免疫病理学改变。并对44例已报道的糖尿病性大疱病病例进行了综述。
