Department of Nursing, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine.
Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine.
Int Heart J. 2024;65(4):778-782. doi: 10.1536/ihj.23-634.
Empty sella syndrome (ESS) is characterized by the herniation of cerebrospinal fluid into the sella, which results in the enlargement of the sella and compression of the pituitary gland. ESS commonly accompanies pituitary dysfunction and abnormal secretion of one or more hormones, which manifests as symptoms like cold intolerance, fatigue, and memory impairment. However, the occurrence of sick sinus syndrome (SSS) in ESS has not been reported. A 66-year-old female patient was admitted to the hospital with complaints of dizziness and fatigue. Electrocardiogram (ECG) revealed sinus arrest, junctional escape rhythm, and a heart rate of 40 bpm. Then, the patient was diagnosed with SSS. Thyroid function test indicated decreased thyroxine levels and slightly elevated thyroid-stimulating hormone levels. Additionally, hyposecretion of cortisol and insulin-like growth factors was observed. Magnetic resonance imaging of the pituitary gland confirmed the diagnosis of ESS. The patient was treated with hydrocortisone and euthyrox, relieving the symptoms of dizziness and fatigue. Thyroid function tests during the follow-up period showed normal hormone levels, and ECG examination revealed no abnormalities.
空蝶鞍综合征（ESS）的特征是脑脊液疝入蝶鞍，导致蝶鞍扩大并压迫垂体。ESS 常伴有垂体功能障碍和一种或多种激素的异常分泌，表现为畏寒、疲劳和记忆力减退等症状。然而，ESS 中窦性停搏综合征（SSS）的发生尚未见报道。一位 66 岁女性患者因头晕和疲劳就诊。心电图（ECG）显示窦性停搏、结性逸搏节律和心率 40 次/分。随后，该患者被诊断为 SSS。甲状腺功能检查显示甲状腺素水平降低，促甲状腺激素水平略有升高。此外，还观察到皮质醇和胰岛素样生长因子分泌不足。垂体磁共振成像（MRI）证实了 ESS 的诊断。患者接受了氢化可的松和左甲状腺素治疗，头晕和疲劳症状得到缓解。随访期间的甲状腺功能检查显示激素水平正常，心电图检查无异常。
