Department for Evidence-Based Medicine and Evaluation, University for Continuing Education Krems, Krems, Austria.
Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Sci Rep. 2024 Jul 31;14(1):17737. doi: 10.1038/s41598-024-67480-1.
The risk of venous thromboembolism (VTE) increases with age. However, the risk of VTE in the setting of long-term care hospitals is understudied. Our objective was to provide data on the prevalence and incidence of VTE in older adults admitted to long-term care hospitals. In this retrospective cohort study, we collected data about chronically ill and multimorbid patients aged 65 years and older from two long-term care hospitals. The primary endpoint of this study was the lifetime prevalence of VTE, and the secondary endpoint was VTE incidence during residency in long-term care hospitals. We analysed data from 1148 patients with a mean age of 84.1 ± 7.9 years, of whom 74.2% were women. The lifetime prevalence of VTE at baseline was 9.6% (95% CI 7.9-11.4). Cumulative incidence of VTE at 1, 2, and 3 years from baseline was estimated at 3.5% (95% CI 2.5-4.7), 4.2% (95% CI 3.1-5.5), and 5.4% (95% CI 4.1-7.0), respectively. Overall, the incidence rate of VTE in our study was 2.82 (95% CI 2.18-3.66) per 100 person-years. The study indicated a considerably high lifetime prevalence and incidence of VTE during residence in long-term care hospital settings, requiring further evaluation in larger prospective studies.
静脉血栓栓塞症(VTE)的风险随年龄增长而增加。然而,长期护理医院中 VTE 的风险研究较少。我们的目的是提供在长期护理医院住院的老年人中 VTE 的患病率和发生率数据。在这项回顾性队列研究中,我们从两家长期护理医院收集了年龄在 65 岁及以上的慢性疾病和多病患者的数据。本研究的主要终点是 VTE 的终身患病率,次要终点是长期护理医院住院期间 VTE 的发生率。我们分析了 1148 名平均年龄为 84.1±7.9 岁的患者的数据,其中 74.2%为女性。基线时 VTE 的终身患病率为 9.6%(95%CI 7.9-11.4)。从基线起 1、2 和 3 年的 VTE 累积发生率估计分别为 3.5%(95%CI 2.5-4.7)、4.2%(95%CI 3.1-5.5)和 5.4%(95%CI 4.1-7.0)。总体而言,VTE 的发生率为每 100 人年 2.82(95%CI 2.18-3.66)。研究表明,在长期护理医院环境中居住期间,VTE 的终身患病率和发生率相当高,需要在更大的前瞻性研究中进一步评估。