Massachusetts General Hospital, Boston, MA, USA.
, 22 Trenton St. Apt 1, Charlestown, MA, 02129, USA.
Surg Endosc. 2024 Oct;38(10):6001-6007. doi: 10.1007/s00464-024-11106-0. Epub 2024 Jul 31.
Hiatal hernia (HH) repairs have been associated with high recurrence rates. This study aimed to investigate if changes in patient's self-reported GERD health-related quality of life (HRQL) scores over time are associated with long-term surgical outcomes.
Retrospective chart reviews were conducted on all patients who had laparoscopic or robotic HH repairs between 2018 and 2022 at a tertiary care center. Information was collected regarding initial BMI, endoscopic HH measurement, surgery, and pre- and post-operative HRQL scores. Repeat imaging at least a year following surgical repair was then evaluated for any evidence of recurrence. Paired t tests were used to compare pre- and post-operative HRQL scores. Wilcoxon ranked-sum tests were used to compare the HRQL scores between the recurrence cohort and non-recurrence cohorts at different time points.
A total of 126 patients underwent HH repairs and had pre- and post-operative HRQL scores. Mesh was used in 23 repairs (18.25%). 42 patients had recorded HH recurrences (33.3%), 35 had no evidence of recurrence (27.7%), and 49 patients (38.9%) had no follow-up imaging. The average pre-operative QOL score was 24.99 (SD ± 14.95) and significantly improved to 5.63 (SD ± 8.51) at 2-week post-op (p < 0.0001). That improvement was sustained at 1-year post-op (mean 7.86, SD ± 8.26, p < 0.0001). The average time between the initial operation and recurrence was 2.1 years (SD ± 1.10). Recurrence was significantly less likely with mesh repairs (p = 0.005). There was no significant difference in QOL scores at 2 weeks, 3 months, 6 months, or 1 year postoperatively between the cohorts (p = NS).
Patients had significant long-term improvement in their HRQL scores after surgical HH repair despite recurrences. The need to re-intervene in patients with HH recurrence should be based on their QOL scores and not necessarily based on established recurrence.
食管裂孔疝(HH)修复术后复发率较高。本研究旨在探讨患者的反流性疾病相关健康相关生活质量(HRQL)评分随时间的变化是否与长期手术结果相关。
对 2018 年至 2022 年在一家三级护理中心接受腹腔镜或机器人 HH 修复术的所有患者进行回顾性图表审查。收集了初始 BMI、内镜 HH 测量、手术以及术前和术后 HRQL 评分的信息。然后,对至少在手术后一年进行的重复影像学检查进行评估,以寻找任何复发的证据。采用配对 t 检验比较术前和术后 HRQL 评分。采用 Wilcoxon 秩和检验比较不同时间点复发组和非复发组的 HRQL 评分。
共有 126 例患者接受了 HH 修复术,并进行了术前和术后 HRQL 评分。有 23 例(18.25%)使用了网片。42 例患者出现 HH 复发(33.3%),35 例患者无复发证据(27.7%),49 例患者(38.9%)无随访影像学检查。术前 QOL 评分平均为 24.99(SD±14.95),术后 2 周显著改善至 5.63(SD±8.51)(p<0.0001)。术后 1 年的改善仍持续(平均 7.86,SD±8.26,p<0.0001)。初次手术与复发之间的平均时间为 2.1 年(SD±1.10)。网状修补术复发的可能性显著降低(p=0.005)。术后 2 周、3 个月、6 个月和 1 年,复发组与非复发组之间的 QOL 评分无显著差异(p=NS)。
尽管存在复发,但患者在接受 HH 修复术后的 HRQL 评分仍有显著的长期改善。对 HH 复发患者进行再次干预的必要性应基于其生活质量评分,而不一定基于既定的复发标准。