Wang Zhenyu, Bright Tim, Irvine Tanya, Thompson Sarah K, Devitt Peter G, Watson David I
Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, Adelaide, South Australia, Australia.
J Gastrointest Surg. 2015 Aug;19(8):1385-90. doi: 10.1007/s11605-015-2807-2. Epub 2015 Mar 31.
Radiological follow-up following repair of large hiatus hernias have identified recurrence rates of 20-30%, although most are small and asymptomatic. Whether patients will eventually develop clinical problems is uncertain. This study evaluated the outcome for individuals identified with an asymptomatic hiatus hernia following previous repair vs. asymptomatic controls.
One hundred fifteen asymptomatic patients who had previously undergone sutured repair of a large hiatus hernia and then underwent barium meal X-ray 6-60 months after surgery within a clinical trial were identified and divided into two cohorts: with (n = 41) vs. without (n = 74) an asymptomatic hernia. Heartburn, dysphagia, and satisfaction with surgery were assessed prospectively using a standardized questionnaire applying analogue scales. Consumption of antisecretory medication and revision surgery were also determined. To determine the natural history of asymptomatic recurrent hiatus hernia, outcomes for the two groups were compared at 1 and 5 years and at most recent (late) follow-up.
Outcomes were available at 1 year for 98.2% and 5 years or the latest follow-up (range 6-237 months) for 100%. Heartburn and dysphagia scores were low and satisfaction scores high in both groups at all follow-up points, but heartburn scores and medication use were higher in the recurrent hernia group. At late follow-up, 94.6% of the recurrent hernia group vs. 98.5% without a hernia regarded their original decision for surgery to be correct. Two patients in recurrent hernia group underwent revision surgery.
Patients with an initially asymptomatic recurrent hiatus hernia are more likely to report heartburn and use antisecretory medication at later follow-up than controls. However, overall clinical outcomes remain good, with high satisfaction and low surgical revision rates. Additional interventions to reduce the risk of recurrence might not be warranted.
大型食管裂孔疝修补术后的影像学随访发现复发率为20%-30%,尽管大多数复发较小且无症状。患者最终是否会出现临床问题尚不确定。本研究评估了既往修补术后发现的无症状食管裂孔疝患者与无症状对照组的结局。
在一项临床试验中,识别出115例曾接受大型食管裂孔疝缝合修补术且术后6-60个月接受了钡餐X线检查的无症状患者,并将其分为两组:有(n = 41)和无(n = 74)无症状疝。使用应用模拟量表的标准化问卷对烧心、吞咽困难和手术满意度进行前瞻性评估。还确定了抗分泌药物的使用情况和翻修手术情况。为了确定无症状复发性食管裂孔疝的自然病程,比较了两组在1年、5年以及最近(晚期)随访时的结局。
98.2%的患者有1年的结局数据,100%的患者有5年或最新随访(范围6-237个月)的结局数据。在所有随访点,两组的烧心和吞咽困难评分均较低,满意度评分较高,但复发性疝组的烧心评分和药物使用更高。在晚期随访时,复发性疝组94.6%的患者与无疝组98.5%的患者认为他们最初的手术决定是正确的。复发性疝组有2例患者接受了翻修手术。
最初无症状的复发性食管裂孔疝患者在后期随访中比对照组更有可能报告烧心并使用抗分泌药物。然而,总体临床结局仍然良好,满意度高,手术翻修率低。可能无需采取额外干预措施来降低复发风险。