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Superior survival with allogeneic hematopoietic stem cell transplantation chemotherapy for high-risk adult acute lymphoblastic leukemia in a PDT-ALL-2016 pediatric-inspired cohort.

作者信息

Chen Junjie, Cai Zihong, Huang Zicong, Lin Jieping, Wang Zhixiang, Ou Jiawang, Xu Xiuli, Tang Bingqing, Ding Chenhao, Li Jia, Lin Ren, Zhang Ting, Xuan Li, Liu Qifa, Zhou Hongsheng

机构信息

Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou.

出版信息

Haematologica. 2024 Dec 1;109(12):4125-4130. doi: 10.3324/haematol.2024.285590.

DOI:10.3324/haematol.2024.285590
PMID:39086299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11609792/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33e0/11609792/6ac2f85ef059/1094125.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33e0/11609792/f8b6b01617b9/1094125.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33e0/11609792/6ac2f85ef059/1094125.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33e0/11609792/f8b6b01617b9/1094125.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33e0/11609792/6ac2f85ef059/1094125.fig2.jpg

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Superior survival with allogeneic hematopoietic stem cell transplantation chemotherapy for high-risk adult acute lymphoblastic leukemia in a PDT-ALL-2016 pediatric-inspired cohort.在一个受儿科启发的PDT-ALL-2016队列中，异基因造血干细胞移植联合化疗治疗高危成人急性淋巴细胞白血病具有更高的生存率。
Haematologica. 2024 Dec 1;109(12):4125-4130. doi: 10.3324/haematol.2024.285590.
2
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本文引用的文献

1
STAT5 phosphorylation plus minimal residual disease defines a novel risk classification in adult B-cell acute lymphoblastic leukaemia.STAT5 磷酸化加上微小残留病定义了成人 B 细胞急性淋巴细胞白血病的一种新的危险度分类。
Br J Haematol. 2024 Aug;205(2):517-528. doi: 10.1111/bjh.19467. Epub 2024 Apr 19.
2
PASS-ALL study of paediatric-inspired versus adult chemotherapy regimens on survival of high-risk Philadelphia-negative B-cell acute lymphoblastic leukaemia with allogeneic haematopoietic stem cell transplantation.PASS-ALL 研究：儿科诱导与成人化疗方案对高危费城阴性 B 细胞急性淋巴细胞白血病患者异基因造血干细胞移植后生存的影响。
Br J Haematol. 2024 Feb;204(2):628-637. doi: 10.1111/bjh.19223. Epub 2023 Dec 5.
3
Clinical Benefit of Autologous Stem Cell Transplantation for Patients with Multiple Myeloma Achieving Undetectable Minimal Residual Disease after Induction Treatment.
诱导治疗后达到微小残留病灶不可检测的多发性骨髓瘤患者自体干细胞移植的临床获益。
Cancer Res Commun. 2023 Sep 6;3(9):1770-1780. doi: 10.1158/2767-9764.CRC-23-0185. eCollection 2023 Sep.
4
NGS better discriminates true MRD positivity for the risk stratification of childhood ALL treated on an MRD-based protocol.NGS 可更好地区分真实的微小残留病灶阳性，有助于基于微小残留病灶的方案治疗的儿童急性淋巴细胞白血病的风险分层。
Blood. 2023 Feb 2;141(5):529-533. doi: 10.1182/blood.2022017003.
5
Haploidentical vs sibling, unrelated, or cord blood hematopoietic cell transplantation for acute lymphoblastic leukemia.单倍体相合与同胞供者、无关供者或脐带血造血干细胞移植治疗急性淋巴细胞白血病的比较。
Blood Adv. 2022 Jan 11;6(1):339-357. doi: 10.1182/bloodadvances.2021004916.
6
Superior survival with pediatric-style chemotherapy compared to myeloablative allogeneic hematopoietic cell transplantation in older adolescents and young adults with Ph-negative acute lymphoblastic leukemia in first complete remission: analysis from CALGB 10403 and the CIBMTR.与清髓性异基因造血细胞移植相比，儿科样化疗可显著提高 Ph 阴性急性淋巴细胞白血病初治完全缓解中老年青少年和年轻成人的生存：CALGB 10403 和 CIBMTR 分析。
Leukemia. 2021 Jul;35(7):2076-2085. doi: 10.1038/s41375-021-01213-5. Epub 2021 Mar 30.
7
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Blood. 2021 Apr 8;137(14):1879-1894. doi: 10.1182/blood.2020007311.
8
Superior survival of unmanipulated haploidentical haematopoietic stem cell transplantation compared with intensive chemotherapy as post-remission treatment for children with very high-risk philadelphia chromosome negative B-cell acute lymphoblastic leukaemia in first complete remission.在首次完全缓解的费城染色体阴性 B 细胞急性淋巴细胞白血病极高危儿童中，未经处理的单倍体相合造血干细胞移植作为缓解后治疗的生存优势优于强化化疗。
Br J Haematol. 2020 Mar;188(5):757-767. doi: 10.1111/bjh.16226. Epub 2019 Nov 14.
9
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Leukemia. 2020 Jan;34(1):283-292. doi: 10.1038/s41375-019-0544-3. Epub 2019 Aug 19.
10
Improving results of allogeneic hematopoietic cell transplantation for adults with acute lymphoblastic leukemia in first complete remission: an analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.提高首次完全缓解的成人急性淋巴细胞白血病患者异基因造血细胞移植的疗效：欧洲血液与骨髓移植学会急性白血病工作组的一项分析
Haematologica. 2017 Jan;102(1):139-149. doi: 10.3324/haematol.2016.145631. Epub 2016 Sep 29.