Bouare Nouhoum, Delwaide Jean
Department of Quality, Hygien, Biosafety/Biosecurity and Pharmacovigilence, National Institute of Public Health, Bamako 1771, Mali.
Department of Gastroenterology and Hepatology, CHULiege, Liege 4000, Belgium.
World J Hepatol. 2024 Jul 27;16(7):980-989. doi: 10.4254/wjh.v16.i7.980.
Cytokines like interleukins (ILs) play important roles in inflammation and innate immune. Yang and Zhang carried out an interesting study related to ILs and hepatic diseases. They described the role of ILs in the pathogenesis and resolution of hepatic disorders. The authors summarized alcohol-related liver disease and virus-induced hepatitis, as far as clinical studies carried out on IL-mediated treatments pertaining to these dysfunctions. This editorial contributes to the review by Yang and Zhang titled, "Interleukins in liver disease treatment", and focuses on therapies mediated by ILs in comorbid liver diseases. The documentary search was conducted on recent pertinent literature, primarily using the Google Scholar and PubMed databases.
白细胞介素(ILs)等细胞因子在炎症和固有免疫中发挥着重要作用。杨和张开展了一项与白细胞介素和肝脏疾病相关的有趣研究。他们阐述了白细胞介素在肝脏疾病发病机制及转归中的作用。作者总结了酒精性肝病和病毒感染性肝炎,以及针对这些功能障碍开展的白细胞介素介导治疗的临床研究。这篇社论是对杨和张题为《肝脏疾病治疗中的白细胞介素》的综述的补充,重点关注白细胞介素介导的合并性肝脏疾病的治疗。文献检索主要利用谷歌学术和PubMed数据库对近期相关文献进行。