Zargar Nazanin, Ashraf Hengameh, Zadsirjan Saeede, Najafi Farhood, Jafari Semnani Siavash, Dianat Omid, Mehrabinia Pegah
Department of Endodontic, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iranian Centre for Endodontic Research, Research Institute for Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran Endod J. 2024;19(3):139-147. doi: 10.22037/iej.v19i3.44301.
One of the most common problems in endodontic treatments is post-treatment pain, and sealers might be one of the factors influencing the degree of pain following root canal therapy. The purpose of this study is to compare pain following endodontic treatment using an AH-26 resin sealer against the Resil experimental sealer in mandibular molars with irreversible pulpitis.
One hundred patients with irreversible pulpitis in the mandibular first or second molar were randomly divided into two groups (=50) based on the type of sealer applied. Two postgraduate students with at least five years of experience treated all patients. All patients had a single root canal treatment. Postoperative pain scores and analgesic consumption were assessed after 6, 12, 24, and 48 hours and 3, 4, 5, 6, and 7 days after the treatment. The data were statistically analyzed by Fisher's exact or Chi-Square test (to compare the distribution of qualitative variables in two groups), repeated measures ANOVA (to compare changes in pain intensity over time in two groups), Boneferronie (for pairwise comparisons), Friedman, Wilcoxon and Mann-Whitney tests (for assessment of the changes in pain scores over time). The generalized estimating equations (GEE) were used for assessing time and group effects.
There was no significant difference in postoperative pain between groups at any of the time points studied (>0.05), and also for patient analgesic consumption between groups (>0.05). Both groups recorded the maximum pain levels in the first 6 hours. For each subsequent day postoperatively, the odds ratio (OR) of not using analgesics was 2.078.
Resil and AH-26 perform similarly in terms of the occurrence and intensity of postoperative pain in mandibular molar teeth with irreversible pulpitis.
根管治疗后最常见的问题之一是治疗后疼痛，而封闭剂可能是影响根管治疗后疼痛程度的因素之一。本研究的目的是比较在下颌磨牙不可逆性牙髓炎患者中，使用AH - 26树脂封闭剂与Resil实验性封闭剂进行根管治疗后的疼痛情况。
100名下颌第一或第二磨牙患有不可逆性牙髓炎的患者，根据所使用封闭剂的类型随机分为两组（每组n = 50）。两名至少有五年经验的研究生对所有患者进行治疗。所有患者均接受单根管治疗。在治疗后6、12、24和48小时以及3、4、5、6和7天评估术后疼痛评分和镇痛药消耗量。数据通过Fisher精确检验或卡方检验进行统计学分析（以比较两组定性变量的分布），重复测量方差分析（以比较两组疼痛强度随时间的变化），Bonferroni检验（用于两两比较），Friedman检验、Wilcoxon检验和Mann - Whitney检验（用于评估疼痛评分随时间的变化）。使用广义估计方程（GEE）评估时间和组效应。
在任何研究的时间点，两组之间的术后疼痛均无显著差异（P>0.05），两组之间患者的镇痛药消耗量也无显著差异（P>0.05）。两组在最初6小时内疼痛水平最高。术后随后的每一天，不使用镇痛药的优势比（OR）为2.078。
在患有不可逆性牙髓炎的下颌磨牙中，Resil和AH - 26在术后疼痛的发生率和强度方面表现相似。
