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基于生物活性玻璃、生物陶瓷和环氧胺树脂的根管封闭剂对根管充填后疼痛的影响:一项双盲随机对照试验。

The effect of bioactive glass-based, bioceramic based and epoxy amine resin based root canal sealers on post-obturation pain: A double blinded randomized controlled trial.

作者信息

Nagpal Ritesh, Taneja Sonali, Bhalla Vidhi Kiran

机构信息

Department of Conservative Dentistry and Endodontics, ITS Dental College, Ghaziabad, Uttar Pradesh, India.

出版信息

J Conserv Dent Endod. 2024 Jun;27(6):591-597. doi: 10.4103/JCDE.JCDE_115_24. Epub 2024 Jun 6.

DOI:10.4103/JCDE.JCDE_115_24
PMID:38989484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11232765/
Abstract

AIM

The aim of this study was to compare the effect of two calcium silicate-based and an epoxy resin-based root canal sealers on postoperative pain and analgesic intake following single-visit root canal treatment.

MATERIALS AND METHOD

Ninety patients with at least one first or second molar tooth diagnosed as symptomatic irreversible pulpitis and symptomatic apical periodontitis were selected and allocated into three groups (n=30) according to the sealer used. Root canals were prepared using Protaper Gold instruments (Dentsply Sirona) in a crown down technique and irrigated with 2.5% NaOCl (Calyx, India) and saline solution. Root canal filling was then accomplished with a single cone obturation technique and treated in a single visit by the same endodontist. Patients were told to use a Visual Analog Scale (VAS) to rate their postoperative pain severity as none, minimal, moderate, or severe after 6 h, 24 h, 48 h, 5 days and 7 days following obturation using the appropriate sealers. The need for analgesic intake was also recorded. The data were statistically analyzed.

RESULTS

Results showed a significant difference among the studied groups. Bio-C Sealer Ion+ reported the least pain score followed by Nishika Canal Sealer BG and AH plus sealer at all the time intervals recorded. The intergroup analysis, revealed was a significant difference in postoperative pain at 6 h (p=0.000) and 24 h (p = 0.028), but not at 48 h, 5 day or 7 days (P > 0.05). VAS ratings for all the three groups decreased over time. Also, there were significant differences between the means of analgesic intake among 3 groups (p=0.022). Analgesic intake in group BIO-C Sealer Ion+ is significantly lesser than AH Plus and Nishika Canal Sealer BG group.

CONCLUSION

Calcium silicate-based sealer (Nishika Canal Sealer BG and Bio-C Sealer Ion+) resulted in significantly lower levels of pain as compared to epoxy resin-based sealer (AH Plus) at 6h and 24-h interval, there was no significant difference in postoperative pain occurrence at 48-h, 5 day and 7-day period. The analgesic intake in Bio-C Sealer Ion+ group is significantly lesser than Nishika Canal Sealer BG and AH Plus group.

摘要

目的

本研究旨在比较两种硅酸钙基根管封闭剂和一种环氧树脂基根管封闭剂在单次就诊根管治疗后对术后疼痛和镇痛药物摄入量的影响。

材料与方法

选取90例至少有一颗第一或第二磨牙被诊断为有症状的不可逆性牙髓炎和有症状的根尖周炎的患者,根据所使用的封闭剂分为三组(n = 30)。采用冠向下技术使用Protaper Gold器械(登士柏西诺德公司)预备根管,并用2.5%次氯酸钠(印度卡利克斯公司)和生理盐水冲洗。然后采用单锥充填技术完成根管充填,由同一位牙髓病医生进行单次就诊治疗。告知患者在使用相应封闭剂充填后6小时、24小时、48小时、5天和7天,使用视觉模拟评分法(VAS)将术后疼痛严重程度评为无、轻微、中度或重度。还记录了镇痛药物的使用需求。对数据进行统计学分析。

结果

结果显示研究组之间存在显著差异。在所有记录的时间间隔内,Bio-C Sealer Ion+的疼痛评分最低,其次是Nishika Canal Sealer BG和AH plus封闭剂。组间分析显示,术后6小时(p = 0.000)和24小时(p = 0.028)的疼痛存在显著差异,但在48小时、5天或7天无显著差异(P > 0.05)。三组的VAS评分均随时间下降。此外,三组之间的镇痛药物摄入量均值也存在显著差异(p = 0.022)。Bio-C Sealer Ion+组的镇痛药物摄入量显著低于AH Plus组和Nishika Canal Sealer BG组。

结论

在6小时和24小时的时间间隔内,与环氧树脂基封闭剂(AH Plus)相比,硅酸钙基封闭剂(Nishika Canal Sealer BG和Bio-C Sealer Ion+)导致的疼痛水平显著更低,在48小时、5天和7天的时间段内术后疼痛发生率无显著差异。Bio-C Sealer Ion+组的镇痛药物摄入量显著低于Nishika Canal Sealer BG组和AH Plus组。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d3b/11232765/c4b72e984662/JCDE-27-591-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d3b/11232765/c4b72e984662/JCDE-27-591-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d3b/11232765/c4b72e984662/JCDE-27-591-g002.jpg

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