Carmona Alexis L, Fayek Sameh A
Medicine, University of California (UC) Riverside School of Medicine, Riverside, USA.
Surgery, University of North Texas Health Science Center, Fort Worth, USA.
Cureus. 2024 Jul 1;16(7):e63603. doi: 10.7759/cureus.63603. eCollection 2024 Jul.
Solid pseudopapillary neoplasms (SPNs) of the pancreas are rare tumors that predominantly affect young females and are typically located in the body and tail of the pancreas. Here, we present the case of a 59-year-old male with a large, heavily calcified SPN in the pancreatic head. His surgical history includes an aborted pancreaticoduodenectomy due to vascular involvement, followed by a gastrojejunostomy. Twenty years after the initial discovery, a pancreaticoduodenectomy was performed - the first of its kind - where the pancreas was completely atrophied, and no pancreaticojejunostomy was performed. Histological examination revealed typical features of SPN. This case demonstrates that even with relatively large lesions in a male patient over an extended duration, SPNs can still exhibit favorable features, highlighting the absence of specific preoperative markers for aggressive tumors. Therefore, unless there is an absolute contraindication, complete resection of all SPNs remains advisable.
胰腺实性假乳头状肿瘤（SPN）是一种罕见肿瘤，主要影响年轻女性，通常位于胰腺体部和尾部。在此，我们报告一例59岁男性患者，其胰头部有一个巨大且钙化严重的SPN。他的手术史包括因血管受累而中止的胰十二指肠切除术，随后进行了胃空肠吻合术。在最初发现20年后，进行了首例胰十二指肠切除术，此时胰腺已完全萎缩，未进行胰空肠吻合术。组织学检查显示为SPN的典型特征。该病例表明，即使男性患者存在较大病变且病程较长，SPN仍可表现出良好特征，突出了侵袭性肿瘤缺乏特异性术前标志物这一情况。因此，除非有绝对禁忌证，对所有SPN进行完整切除仍是可取的。
