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成功取出植入25年后的六根左炔诺孕酮硅橡胶皮下植入剂（诺普兰）：一例报告

Successful Removal of Six Levonorgestrel Silastic Subcutaneous Implants (Norplant) 25 Years After Insertion: A Case Report.

作者信息

Old Evan A, Gajarawala Shilpa, Knight Dacre R, Pak Kaitlyn, Carrubba Aakriti R

机构信息

Department of Internal Medicine, Mayo Clinic, Jacksonville, USA.

Department of Medical and Surgical Gynecology, Mayo Clinic, Jacksonville, USA.

出版信息

Cureus. 2024 Jul 1;16(7):e63585. doi: 10.7759/cureus.63585. eCollection 2024 Jul.

DOI:10.7759/cureus.63585
PMID:39087147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11290371/
Abstract

Levonorgestrel-releasing silastic implants are a form of subdermal contraception that utilizes implanted silastic rods to release levonorgestrel, providing long-acting reversible contraception over an extended period of time. This case report presents a female who had lost a significant amount of weight after receiving levonorgestrel-releasing implants 25 years prior. During the elapsed period, the rods were palpable and uncomfortable. She had previously been unable to find a provider willing to remove the implants. This case highlights the possible complications surrounding the removal of levonorgestrel silastic subcutaneous implants and the careful consideration required when the implant has been in place for an extended period.

摘要

左炔诺孕酮缓释硅橡胶植入剂是一种皮下避孕方式，它利用植入的硅橡胶棒释放左炔诺孕酮，在较长一段时间内提供长效可逆避孕效果。本病例报告介绍了一名女性，她在25年前接受左炔诺孕酮缓释植入剂后体重显著减轻。在此期间，这些棒状物可触及且令人不适。她此前一直无法找到愿意取出植入剂的医疗服务提供者。本病例突出了左炔诺孕酮硅橡胶皮下植入剂取出可能存在的并发症，以及植入剂长期留存时所需的谨慎考量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/631c4c0688ef/cureus-0016-00000063585-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/74147eaff20f/cureus-0016-00000063585-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/a6b750b5ec65/cureus-0016-00000063585-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/42056b14a734/cureus-0016-00000063585-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/84c37de6fdf9/cureus-0016-00000063585-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/631c4c0688ef/cureus-0016-00000063585-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/74147eaff20f/cureus-0016-00000063585-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/a6b750b5ec65/cureus-0016-00000063585-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/42056b14a734/cureus-0016-00000063585-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/84c37de6fdf9/cureus-0016-00000063585-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/11290371/631c4c0688ef/cureus-0016-00000063585-i05.jpg

相似文献

1
Successful Removal of Six Levonorgestrel Silastic Subcutaneous Implants (Norplant) 25 Years After Insertion: A Case Report.成功取出植入25年后的六根左炔诺孕酮硅橡胶皮下植入剂（诺普兰）：一例报告
Cureus. 2024 Jul 1;16(7):e63585. doi: 10.7759/cureus.63585. eCollection 2024 Jul.
2
Hormonal implants: contraception for a new century.激素植入剂：新世纪的避孕方法。
Am J Obstet Gynecol. 1994 May;170(5 Pt 2):1536-43. doi: 10.1016/s0002-9378(94)05016-7.
3
Norplant contraceptive implants: rods versus capsules.诺普兰避孕植入剂：棒剂与胶囊剂
Contraception. 1987 Sep;36(3):305-16. doi: 10.1016/0010-7824(87)90100-4.
4
Norplant-2 subdermal contraceptive system: experience in Taiwan.Norplant-2皮下避孕系统：台湾地区的经验
J Formos Med Assoc. 1993 May;92(5):446-50.
5
Subdermal contraceptive implants.皮下避孕植入剂
J Steroid Biochem Mol Biol. 1995 Jun;53(1-6):223-6. doi: 10.1016/0960-0760(95)00051-z.
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Contraception with subdermal implants releasing levonorgestrel. A clinical and pharmacological study.皮下植入左炔诺孕酮的避孕方法：一项临床与药理学研究
Acta Obstet Gynecol Scand Suppl. 1987;142:1-45.
7
Levonorgestrel plasma levels during continuous administration with different models of subdermal implants.不同型号皮下植入剂连续给药期间左炔诺孕酮的血浆水平。
Contraception. 1983 Feb;27(2):123-30. doi: 10.1016/0010-7824(83)90083-5.
8
Subdermal progestin implant contraception.皮下孕激素植入避孕法
Curr Opin Obstet Gynecol. 1991 Aug;3(4):470-6.
9
Rates and outcomes of planned pregnancy after use of Norplant capsules, Norplant II rods, or levonorgestrel-releasing or copper TCu 380Ag intrauterine contraceptive devices.使用诺普兰胶囊、诺普兰Ⅱ型棒、左炔诺孕酮释放宫内节育器或铜质TCu 380Ag宫内节育器后计划妊娠的发生率及结局。
Am J Obstet Gynecol. 1992 Apr;166(4):1208-13. doi: 10.1016/s0002-9378(11)90607-3.
10
Levonorgestrel subdermal implants (Norplant) for long-term contraception.左炔诺孕酮皮下植入剂（诺普兰）用于长效避孕。
MCN Am J Matern Child Nurs. 1991 Jul-Aug;16(4):232. doi: 10.1097/00005721-199107000-00016.

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