• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

疑似甲状旁腺癌患者双膦酸盐诱导的眼眶蜂窝织炎：一例报告

Bisphosphonate-Induced Orbital Cellulitis in a Patient With Suspected Parathyroid Carcinoma: A Case Report.

作者信息

McKenna Teodora, McKenna Dominic E, Fernandes Vinson, Korda Marian, Bradley Una

机构信息

Otolaryngology - Head and Neck Surgery, Queen's University Medical School, Belfast, GBR.

Otolaryngology - Head and Neck Surgery, Southern Health and Social Care Trust, Craigavon, GBR.

出版信息

Cureus. 2024 Jul 1;16(7):e63577. doi: 10.7759/cureus.63577. eCollection 2024 Jul.

DOI:10.7759/cureus.63577
PMID:39087171
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11290043/
Abstract

Bisphosphonates are widely used for a number of metabolic bone conditions. Orbital inflammation is a very rare side effect of bisphosphonate therapy that can risk permanent visual loss. We describe the complex case and successful treatment of a 79-year-old man who developed orbital cellulitis following the use of intravenous pamidronate disodium for severe hypercalcaemia. The challenges regarding the diagnosis of parathyroid carcinoma are also discussed.

摘要

双膦酸盐被广泛用于多种代谢性骨病。眼眶炎症是双膦酸盐治疗非常罕见的副作用，可能导致永久性视力丧失。我们描述了一例复杂病例及成功治疗过程，一名79岁男性在使用静脉注射帕米膦酸二钠治疗严重高钙血症后发生眼眶蜂窝织炎。文中还讨论了甲状旁腺癌诊断方面的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/558076f1d9ec/cureus-0016-00000063577-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/768a74acdd5f/cureus-0016-00000063577-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/ec1955a98b3f/cureus-0016-00000063577-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/810d5157e613/cureus-0016-00000063577-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/3142dadf042e/cureus-0016-00000063577-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/6d33bbdf4589/cureus-0016-00000063577-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/b18047afc5a1/cureus-0016-00000063577-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/44c9b4adef2a/cureus-0016-00000063577-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/62223025801f/cureus-0016-00000063577-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/558076f1d9ec/cureus-0016-00000063577-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/768a74acdd5f/cureus-0016-00000063577-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/ec1955a98b3f/cureus-0016-00000063577-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/810d5157e613/cureus-0016-00000063577-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/3142dadf042e/cureus-0016-00000063577-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/6d33bbdf4589/cureus-0016-00000063577-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/b18047afc5a1/cureus-0016-00000063577-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/44c9b4adef2a/cureus-0016-00000063577-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/62223025801f/cureus-0016-00000063577-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f98a/11290043/558076f1d9ec/cureus-0016-00000063577-i09.jpg

相似文献

1
Bisphosphonate-Induced Orbital Cellulitis in a Patient With Suspected Parathyroid Carcinoma: A Case Report.疑似甲状旁腺癌患者双膦酸盐诱导的眼眶蜂窝织炎：一例报告
Cureus. 2024 Jul 1;16(7):e63577. doi: 10.7759/cureus.63577. eCollection 2024 Jul.
2
Two cases of spontaneous remission of primary hyperparathyroidism due to auto-infarction: different management and their outcomes.两例因自梗死导致原发性甲状旁腺功能亢进自发缓解的病例：不同的处理方法及其结果
Endocrinol Diabetes Metab Case Rep. 2019 May 7;2019. doi: 10.1530/EDM-18-0136.
3
A case of bisphosphonate-related osteonecrosis of the maxilla with orbital cellulitis.一例双膦酸盐相关的上颌骨骨坏死伴眶蜂窝织炎。
Ear Nose Throat J. 2025 Jan;104(1):22-24. doi: 10.1177/01455613221086028. Epub 2022 Mar 31.
4
Bisphosphonates for breast cancer.用于乳腺癌的双膦酸盐类药物。
Cochrane Database Syst Rev. 2005 Jul 20(3):CD003474. doi: 10.1002/14651858.CD003474.pub2.
5
Disodium pamidronate in the preoperative treatment of hypercalcemia in patients with primary hyperparathyroidism.帕米膦酸二钠用于原发性甲状旁腺功能亢进患者高钙血症的术前治疗。
Surgery. 1991 Sep;110(3):480-6.
6
Bisphosphonate-Induced Acute Orbital Inflammation in a Patient With Underlying Thyroid Ophthalmopathy.双膦酸盐诱发的急性眼眶炎症在一名患有潜在甲状腺眼病的患者中出现。
Cureus. 2020 Dec 11;12(12):e12024. doi: 10.7759/cureus.12024.
7
Bisphosphonate-Induced Orbital Inflammation: A Case Series and Review.双膦酸盐诱导的眼眶炎症：病例系列及文献综述
Orbit. 2015;34(6):331-5. doi: 10.3109/01676830.2015.1078380. Epub 2015 Nov 5.
8
Exceptional localisation of an ectopic parathyroid adenoma at the level of the hyoid bone.甲状旁腺异位腺瘤在舌骨水平的特殊定位。
BMJ Case Rep. 2014 Jun 11;2014:bcr2013200557. doi: 10.1136/bcr-2013-200557.
9
Bisphosphonates for breast cancer.用于乳腺癌的双膦酸盐类药物。
Cochrane Database Syst Rev. 2002(1):CD003474. doi: 10.1002/14651858.CD003474.
10
A systematic review of the role of bisphosphonates in metastatic disease.双膦酸盐在转移性疾病中作用的系统评价
Health Technol Assess. 2004;8(4):1-176. doi: 10.3310/hta8040.

本文引用的文献

1
Ocular Side Effects of Bisphosphonates: A Review of Literature.双膦酸盐类药物的眼部副作用：文献综述
J Ocul Pharmacol Ther. 2023 Jan-Feb;39(1):3-16. doi: 10.1089/jop.2022.0094. Epub 2022 Nov 21.
2
Osteoporosis, bisphosphonates, and ocular inflammation.骨质疏松症、双膦酸盐与眼部炎症。
Eur J Ophthalmol. 2022 Sep 4:11206721221125022. doi: 10.1177/11206721221125022.
3
Orbital Inflammation Caused by Aminobisphosphonates.氨基双膦酸盐引起的眼眶炎症。
J Ophthalmic Vis Res. 2022 Jan 21;17(1):118-122. doi: 10.18502/jovr.v17i1.10176. eCollection 2022 Jan-Mar.
4
A Review of Current Clinical Concepts in the Pathophysiology, Etiology, Diagnosis, and Management of Hypercalcemia.高钙血症的病理生理学、病因学、诊断和治疗的当前临床概念综述。
Med Sci Monit. 2022 Feb 26;28:e935821. doi: 10.12659/MSM.935821.
5
Bisphosphonate-associated osteonecrosis of the jaw.双膦酸盐相关性颌骨坏死。
Minerva Dent Oral Sci. 2021 Feb;70(1):49-57. doi: 10.23736/S2724-6329.20.04306-X. Epub 2020 Sep 22.
6
Parathyroid cancer: An update.甲状旁腺癌：最新进展。
Cancer Treat Rev. 2020 Jun;86:102012. doi: 10.1016/j.ctrv.2020.102012. Epub 2020 Mar 19.
7
Orbital Compartment Syndrome: An Update With Review Of The Literature.眼眶间隔综合征：文献综述及最新进展
Clin Ophthalmol. 2019 Nov 7;13:2189-2194. doi: 10.2147/OPTH.S180058. eCollection 2019.
8
Stones, Bones, Groans, and Psychic Moans: Primary Hyperparathyroidism Presenting as Surgical Emergency.结石、骨骼、呻吟与精神性呻吟：以外科急症形式表现的原发性甲状旁腺功能亢进症
Cureus. 2019 Jun 25;11(6):e4989. doi: 10.7759/cureus.4989.
9
Bisphosphonate-induced osteonecrosis of the ear canal: our experience and a review of the literature.双膦酸盐类药物诱发的耳道骨坏死：我们的经验及文献综述
J Laryngol Otol. 2018 Apr;132(4):372-374. doi: 10.1017/S0022215118000324. Epub 2018 Feb 28.
10
Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus.原发性甲状旁腺功能亢进症：关于评估、诊断和管理的综述与建议。加拿大及国际共识。
Osteoporos Int. 2017 Jan;28(1):1-19. doi: 10.1007/s00198-016-3716-2. Epub 2016 Sep 9.