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乳腺乳头状癌罕见病例

Unusual Case of Papillary Carcinoma of the Breast.

作者信息

Dnyanmote Anuradha, M P Himashree

机构信息

Department of General Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND.

出版信息

Cureus. 2024 Jul 1;16(7):e63568. doi: 10.7759/cureus.63568. eCollection 2024 Jul.

Abstract

Papillary carcinoma of the breast represents a distinct subtype of breast cancer characterized by its unique clinical and histopathological features. It is seen predominantly affecting post-menopausal women. Overall, papillary carcinoma has a low prevalence. Histologically, papillary carcinoma is characterized by the presence of papillae-like structures lined by epithelial cells and supported by fibrovascular cores, appearing like a dual-layered epithelium. The clinical, epidemiological, and pathological characteristics of papillary carcinoma of the breast are not widely described in the existing literature. The gold standard for diagnosis of carcinoma breast of any type remains a core needle biopsy, but in our case, the diagnosis of papillary carcinoma was made in the final histopathology specimen. Treatment strategies for papillary carcinoma include surgical excision with or without axillary dissection followed by adjuvant chemo-radiotherapy depending on the immunohistochemistry and tumor characteristics, but there appear multiple variations in the management of more common NOS (not otherwise specified) type and the papillary carcinoma of the breast. We present a case report of this papillary carcinoma of the breast.

摘要

乳腺乳头状癌是乳腺癌的一种独特亚型,具有独特的临床和组织病理学特征。它主要见于绝经后女性。总体而言,乳头状癌的患病率较低。在组织学上,乳头状癌的特征是存在由上皮细胞排列并由纤维血管核心支撑的乳头状结构,看起来像双层上皮。现有文献中对乳腺乳头状癌的临床、流行病学和病理特征描述并不广泛。诊断任何类型乳腺癌的金标准仍然是粗针活检,但在我们的病例中,乳头状癌的诊断是在最终的组织病理学标本中做出的。乳头状癌的治疗策略包括手术切除,可伴有或不伴有腋窝清扫,然后根据免疫组化和肿瘤特征进行辅助放化疗,但在更常见的未另行指定(NOS)型和乳腺乳头状癌的管理方面存在多种差异。我们报告一例乳腺乳头状癌病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcf/11289855/5844f0a37aa5/cureus-0016-00000063568-i01.jpg

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