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肠螺旋体病:四种不同临床表现的病例。

Intestinal spirochetosis: four cases with different clinical presentations.

机构信息

Medicina Digestiva, Hospital Francesc de Borja , España.

Medicina Digestiva, Hospital Francesc de Borja, España.

出版信息

Rev Esp Enferm Dig. 2024 Oct;116(10):564-565. doi: 10.17235/reed.2024.10621/2024.

DOI:10.17235/reed.2024.10621/2024
PMID:39087657
Abstract

We present 4 clinical cases of intestinal spirochetosis. The first one presents with chronic diarrhea, and spirochetes are detected in random biopsies. The second is homosexual, HIV+, presents rectal bleeding, colonoscopy shows a straight ulcer and spirochete biopsies show negative treponema PCR. The third was also homosexual, HIV+, asymptomatic, with a chance finding of spirochetosis. The last case is also a chance histological diagnosis in a patient with inactive ulcerative colitis without lesions. Intestinal spirochetosis appears to be transmitted sexually and by consumption of contaminated water. The majority are asymptomatic cases but could cause lesions including ulcerations and symptoms. Treatment is only recommended in symptomatic or immunosuppressed patients. It must be distinguished from lesions caused by Treponema pallidum.

摘要

我们呈现了 4 例肠道螺旋体病的临床病例。第一例表现为慢性腹泻,在随机活检中检测到螺旋体。第二例是同性恋者,HIV+,出现直肠出血,结肠镜检查显示直溃疡,螺旋体活检显示阴性梅毒 PCR。第三例也是同性恋者,HIV+,无症状,偶然发现螺旋体病。最后一例也是一位无病变的非活动溃疡性结肠炎患者的偶然组织学诊断。肠道螺旋体病似乎通过性传播和食用受污染的水传播。大多数是无症状病例,但可能导致病变,包括溃疡和症状。仅推荐在有症状或免疫抑制的患者中进行治疗。必须与梅毒螺旋体引起的病变区分开来。

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1
Intestinal spirochetosis: four cases with different clinical presentations.肠螺旋体病:四种不同临床表现的病例。
Rev Esp Enferm Dig. 2024 Oct;116(10):564-565. doi: 10.17235/reed.2024.10621/2024.
2
Intestinal spirochetosis and chronic watery diarrhea: clinical and histological response to treatment and long-term follow up.肠道螺旋体病与慢性水样腹泻:治疗的临床及组织学反应与长期随访
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[Immunohistochemical diagnosis of colonic spirochetosis with anti-treponema antibody in patients consulting for chronic diarrhea. Results of a prospective study conducted in 137 patients].[应用抗梅毒螺旋体抗体对慢性腹泻患者进行结肠螺旋体病的免疫组织化学诊断。对137例患者进行的前瞻性研究结果]
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Intestinal spirochetosis: a poorly understood infection causing chronic diarrhea.肠道螺旋体病:一种了解甚少的导致慢性腹泻的感染性疾病。
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[Colorectal spirochetosis, a possible but unusual cause of chronic diarrhea?].[结肠螺旋体病,慢性腹泻的一个可能但不常见的病因?]
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[Intestinal spirochetosis in homosexuals infected with HIV. 3 cases].[感染人类免疫缺陷病毒的同性恋者的肠道螺旋体病。3例报告]
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Clinicopathologic study of intestinal spirochetosis in Japan with special reference to human immunodeficiency virus infection status and species types: analysis of 5265 consecutive colorectal biopsies.日本肠道螺旋体病的临床病理研究:特别关注人类免疫缺陷病毒感染状况及菌种类型——对5265例连续结直肠活检的分析
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[Intestinal spirochetosis: A rare cause of chronic diarrhea].[肠道螺旋体病:慢性腹泻的罕见病因]
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