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全膝关节和髋关节置换术后急性阿片类药物使用在英语水平、种族和族裔方面的差异。

Differences in Acute Postoperative Opioid Use by English Proficiency, Race, and Ethnicity After Total Knee and Hip Arthroplasty.

作者信息

Joo Hyundeok, Nguyen Kevin, Kolodzie Kerstin, Chen Lee-Lynn, Kim Mi-Ok, Manuel Solmaz

机构信息

From the Department of Anesthesia and Perioperative Care, University of California San Francisco School of Medicine, San Francisco, California.

University of California, San Francisco School of Medicine, San Francisco, California.

出版信息

Anesth Analg. 2025 Jan 1;140(1):155-164. doi: 10.1213/ANE.0000000000007068. Epub 2024 Aug 1.

Abstract

BACKGROUND

There is increasing interest in documenting disparities in pain management for racial and ethnic minorities and patients with language barriers. Previous studies have found differential prescription patterns of opioids for racial and ethnic minority group and patients having limited English proficiency (LEP) after arthroplasty. However, there is a knowledge gap regarding how the intersection of these sociodemographic factors is associated with immediate postoperative pain management. This study aimed to explore language and racial-ethnic disparities in short-term opioid utilization after total hip and knee arthroplasty.

METHODS

We conducted a retrospective cohort study of adult patients who underwent total hip and knee arthroplasty from 2015 to 2019 at an urban medical center. The primary predictor variables included LEP status and racial-ethnic category, and the primary outcome variables were oral morphine equivalents (OMEs) during 2 distinct postoperative periods: the first 12 hours after surgery and from the end of surgery to the end of postoperative day (POD) 1. Patient characteristics and perioperative metrics were described by language status, race, and ethnicity using nonparametric tests, as appropriate. We performed an adjusted generalized estimating equation to assess the total effect of the intersection of LEP and racial-ethnic categories on short-term postoperative opioid use in mean ratios (MRs).

RESULTS

This study included a total of 4090 observations, in which 7.9% (323) patients had LEP. Patients reported various racial-ethnic categories, with 72.7% (2975) non-Hispanic White, and minority groups including non-Hispanic Asian and Pacific Islander (AAPI), Hispanic/Latinx, non-Hispanic Black/African American, and Others. Patients self-identifying as non-Hispanic AAPI received fewer OME regardless of LEP status during the first 12 hours postoperatively (MR for English proficient [EP], 0.12 [95% confidence interval, CI, 0.08-0.18]; MR for LEP, 0.22 [95% CI, 0.13-0.37]) and from end of surgery to the end of POD 1 (MR for EP, 0.24 [95% CI, 0.16-0.37]; MR for LEP, 0.42, [95% CI, 0.24-0.73]) than EP non-Hispanic White. Hispanic/Latinx patients with LEP received lower amounts of OME during the first postoperative 12 hours (MR, 0.29; 95% CI, 0.17-0.53) and from end of surgery to the end of POD 1 (MR, 0.42; 95% CI 0.23-0.79) than EP non-Hispanic White. Furthermore, within the non-Hispanic White group, those with LEP received fewer OME within the first 12 hours (MR, 0.33; 95% CI, 0.13-0.83).

CONCLUSIONS

We identified an association between LEP, racial-ethnic identity, and short-term postoperative OME utilization after total knee and hip arthroplasty. The observed differences in opioid utilization imply there may be language and racial-ethnic disparities in acute pain management and perioperative care.

摘要

背景

记录种族和少数民族以及有语言障碍患者在疼痛管理方面的差异受到越来越多的关注。先前的研究发现,在关节置换术后,种族和少数民族群体以及英语水平有限(LEP)的患者在阿片类药物处方模式上存在差异。然而,关于这些社会人口学因素的交叉点与术后即刻疼痛管理之间的关联,目前存在知识空白。本研究旨在探讨全髋关节和膝关节置换术后短期阿片类药物使用中的语言和种族差异。

方法

我们对2015年至2019年在一家城市医疗中心接受全髋关节和膝关节置换术的成年患者进行了一项回顾性队列研究。主要预测变量包括LEP状态和种族类别,主要结局变量是术后两个不同时间段的口服吗啡当量(OME):术后前12小时以及从手术结束到术后第1天结束。根据语言状态、种族和民族,酌情使用非参数检验描述患者特征和围手术期指标。我们进行了调整后的广义估计方程,以评估LEP和种族类别交叉点对术后短期阿片类药物使用的平均比率(MR)的总体影响。

结果

本研究共纳入4090例观察对象,其中7.9%(323例)患者有LEP。患者报告了不同的种族类别,其中72.7%(2975例)为非西班牙裔白人,少数群体包括非西班牙裔亚裔和太平洋岛民(AAPI)、西班牙裔/拉丁裔、非西班牙裔黑人/非裔美国人以及其他群体。自我认定为非西班牙裔AAPI的患者,无论LEP状态如何,在术后前12小时(英语熟练[EP]者的MR为0.12[95%置信区间,CI,0.08 - 0.18];LEP者的MR为0.22[95%CI,0.13 - 0.37])以及从手术结束到术后第1天结束(EP者的MR为0.24[95%CI,0.16 - 0.37];LEP者的MR为0.42,[95%CI,0.24 - 0.73])接受的OME均少于EP非西班牙裔白人。有LEP的西班牙裔/拉丁裔患者在术后前12小时(MR,0.29;95%CI,0.17 - 0.53)以及从手术结束到术后第1天结束(MR,0.42;95%CI 0.23 - 0.79)接受的OME量低于EP非西班牙裔白人。此外,在非西班牙裔白人组中,有LEP的患者在术后前12小时接受的OME较少(MR,0.33;95%CI,0.13 - 0.83)。

结论

我们发现LEP、种族身份与全膝关节和髋关节置换术后短期术后OME使用之间存在关联。观察到的阿片类药物使用差异表明,在急性疼痛管理和围手术期护理中可能存在语言和种族差异。

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