35公斤儿童ABO血型不相容心脏移植的双重免疫吸附疗法
Dual immunoadsorption for ABO-incompatible heart transplantation in a 35 kg child.
作者信息
Crook Richard, Cohen Marc, Mimic Branko, Fenton Matthew, Issitt Richard
机构信息
Department of Perfusion, Great Ormond Street Hospital for Children, London, UK.
Department of Anaesthetics, Great Ormond Street Hospital for Children, London, UK.
出版信息
Perfusion. 2025 May;40(4):1054-1056. doi: 10.1177/02676591241268428. Epub 2024 Aug 1.
Intraoperative anti-A/B immunoadsorption (ABO-IA) was recently introduced for ABO-incompatible (ABOi) heart transplantation. Here we report the first case of a patient transplanted with ABO-IA, that was of an age and weight that required two ABO-IA columns run in parallel, to enable the reduction in antibody titres to a sufficiently low level in the time available during implantation of the donor organ.
术中抗A/B免疫吸附（ABO-IA）最近被引入用于ABO血型不相容（ABOi）心脏移植。在此，我们报告首例接受ABO-IA移植的患者，该患者的年龄和体重需要并行运行两根ABO-IA柱，以便在供体器官植入期间的可用时间内将抗体滴度降低到足够低的水平。
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