Groothuis D R, Blasberg R G
Neurol Clin. 1985 Nov;3(4):801-16.
This article demonstrates that drug delivery to brain tumors is a function of both drug properties and tumor properties and that both must be considered in planning chemotherapeutic strategies. The range of variability in drug and tumor properties and the effect of each on drug delivery are illustrated.
本文表明，向脑肿瘤递送药物是药物特性和肿瘤特性共同作用的结果，在制定化疗策略时必须同时考虑这两个因素。文中阐述了药物和肿瘤特性的变异性范围以及各自对药物递送的影响。
