CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology and Behavioral Science, Zhejiang University, Hangzhou, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
Asian J Psychiatr. 2024 Oct;100:104188. doi: 10.1016/j.ajp.2024.104188. Epub 2024 Jul 29.
Empirical findings suggested that anhedonia, a reduced capability to access pleasure and a core symptom in both schizophrenia and the major depressive disorder, can be present in people with high levels of social anhedonia and people with subsyndromal depression. Few studies have adopted a multidimensional framework to investigate anhedonia in these subclinical samples. We recruited 35 participants with high social anhedonia (SA), 53 participants with subsyndromal depression (SD), 20 participants with co-occurrence of both traits (CO), and 47 participants with low levels of both traits (CN) to complete a self-report questionnaire capturing the pleasure experience, and the Monetary Incentives Delay (MID) Task and the Social Incentives Delay (SID) Task capturing the motivation of reward. Results indicated that people with SA, SD and CO exhibited lower abstract anticipatory pleasure compared to CN. Moreover, people with SD and CO exhibited specific impairment in response to social incentives. Together, our findings characterized the multidimensional features of anhedonia performances of subclinical samples with SA, SD and CO, which may contribute to the formulation of early identification of at-risk groups.
实证研究结果表明,快感缺失,一种获取快乐的能力降低,是精神分裂症和重度抑郁症的核心症状,在社会快感缺失程度较高的人群和亚临床抑郁人群中都可能存在。很少有研究采用多维框架来研究这些亚临床样本中的快感缺失。我们招募了 35 名社会快感缺失程度较高的参与者(SA)、53 名亚临床抑郁的参与者(SD)、20 名同时存在两种特征的参与者(CO)和 47 名两种特征水平较低的参与者(CN),让他们完成一个自我报告问卷,以捕捉愉悦体验,以及金钱激励延迟(MID)任务和社会激励延迟(SID)任务,以捕捉奖励的动机。结果表明,与 CN 相比,SA、SD 和 CO 参与者的抽象预期愉悦感较低。此外,SD 和 CO 参与者在对社会激励的反应方面表现出特定的障碍。总之,我们的研究结果描述了具有 SA、SD 和 CO 的亚临床样本的快感缺失表现的多维特征,这可能有助于制定高危人群的早期识别方案。