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肾移植术后可逆性肾功能不全和动脉高血压:移植肾动脉狭窄及卡托普利-呋塞米联合应用的作用

[Reversible renal insufficiency and arterial hypertension after renal transplantation: role of transplant artery stenosis and a captopril-furosemide combination].

作者信息

Suc J M, Vernier I, Durand D, Giraud P, Segonds-Modesto A, Sarramon J P

出版信息

Nephrologie. 1985;6(3):155-8.

PMID:3908959
Abstract

Acute renal failure after captopril therapy in patients with transplant artery stenosis is well known. The study of a new observation may stress three particular points: 1) Diagnosis may be difficult just after transplantation in case of initial acute renal failure. 2) Renal function rapidly improved after withdrawing captopril and furosemide; after surgical treatment of the stenosis, a new course of captopril therapy was possible without any decrease of glomerular filtration rate. 3) A critical fall in filtration fraction seems to be the essential mechanism of renal failure, but specific interstitial lesions of the transplant showed on kidney biopsies, might be discussed.

摘要

移植肾动脉狭窄患者在接受卡托普利治疗后发生急性肾衰竭是众所周知的。一项新观察性研究可能强调三个特殊要点:1)在移植术后初期发生急性肾衰竭时,诊断可能困难。2)停用卡托普利和呋塞米后肾功能迅速改善;在对狭窄进行手术治疗后,可重新开始卡托普利治疗,而肾小球滤过率无任何下降。3)滤过分数的严重下降似乎是肾衰竭的基本机制,但对于肾活检显示的移植肾特异性间质病变,可能存在争议。

相似文献

1
[Reversible renal insufficiency and arterial hypertension after renal transplantation: role of transplant artery stenosis and a captopril-furosemide combination].肾移植术后可逆性肾功能不全和动脉高血压:移植肾动脉狭窄及卡托普利-呋塞米联合应用的作用
Nephrologie. 1985;6(3):155-8.
2
[Hypertension and stenosis of the graft artery: effects of conversion enzyme inhibition].
Arch Mal Coeur Vaiss. 1986 Jun;79(6):892-5.
3
[Renal insufficiency after administration of captopril in renal artery stenosis with a single kidney or bilateral stenosis is not compulsory].在单肾肾动脉狭窄或双侧肾动脉狭窄患者中,使用卡托普利后出现肾功能不全并非必然。
Arch Mal Coeur Vaiss. 1984 Oct;77(11):1272-7.
4
[Predictability of post-captopril acute renal failure in hypertension with renal artery stenosis of a single kidney or bilateral stenosis].
Arch Mal Coeur Vaiss. 1986 Jun;79(6):888-91.
5
Captopril-induced deterioration of graft function in patients with a transplant renal artery stenosis.
Proc Eur Dial Transplant Assoc. 1983;20:325-30.
6
Captopril-associated granulocytopenia in hypertension after renal transplantation.肾移植后高血压患者中与卡托普利相关的粒细胞减少症
Clin Nephrol. 1984 Dec;22(6):314-6.
7
Captopril-induced acute renal failure in a kidney transplant recipient.卡托普利诱发肾移植受者急性肾衰竭。
Clin Nephrol. 1983 Jun;19(6):320-1.
8
Deterioration of renal function after converting enzyme inhibition in a patient with renal artery stenosis after transplantation.
Neth J Med. 1984;27(1):10-3.
9
Does captopril reduce renal function in renovascular disease by postglomerular vasodilatation?
J Hypertens Suppl. 1985 Nov;3(2):S139-41.
10
Acute effect of captopril on single kidney glomerular filtration rate in arterial hypertension.卡托普利对动脉高血压患者单肾肾小球滤过率的急性影响。
J Hypertens Suppl. 1985 Nov;3(2):S137-8.