Burn Department, Shriners Children's Northern California, 2425 Stockton Boulevard, Sacramento, CA 95817, USA; Emeritus, Department of Surgery, University of California, Davis, CA, USA.
Adv Surg. 2024 Sep;58(1):1-17. doi: 10.1016/j.yasu.2024.04.001. Epub 2024 May 8.
The optimal treatment of burn shock is still unresolved. The problem of "fluid creep" continues despite modern devices that fail to improve outcomes over hourly urine output. Colloids, especially albumin, reduce fluid requirements. Albumin can be used either immediately at the start of resuscitation, or as a "rescue" when crystalloid use is excessive. Several studies confirm that when crystalloid resuscitation is "out of control" the majority of caregivers will add albumin to reduce fluid rates. A multi-center trial is underway comparing crystalloids with albumin to confirm the benefit of colloids. The next question is whether albumin or plasma is as the better colloid choice.
烧伤休克的最佳治疗方法仍未解决。尽管现代设备未能改善每小时尿量的结果,但“液体渗出”问题仍然存在。胶体,特别是白蛋白,可减少液体需求。白蛋白可在复苏开始时立即使用,也可在晶体液使用过多时作为“抢救”措施。几项研究证实,当晶体液复苏“失控”时,大多数护理人员会添加白蛋白以降低液体速度。一项比较晶体液与白蛋白的多中心试验正在进行中,以确认胶体的益处。下一个问题是白蛋白或血浆作为更好的胶体选择。