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评价肺移植术后气肿性肠病作为一种并发症。

Evaluation of pneumatosis intestinalis as a complication of lung transplantation.

机构信息

Servicio de Radiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain.

Servicio de Radiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain.

出版信息

Radiologia (Engl Ed). 2024 Jul-Aug;66(4):314-325. doi: 10.1016/j.rxeng.2023.01.013. Epub 2024 Jul 17.

Abstract

INTRODUCTION

Pneumatosis intestinalis is a radiological finding characterized by the presence of gas in the bowel wall that is associated with multiple entities. Our aim is to know its incidence in lung transplant patients, its physiopathology and its clinical relevance.

METHODS

A search of patients with pneumatosis intestinalis was performed in the database of the Lung Transplant Unit of our hospital. The presence of pneumatosis after transplantation was confirmed in all of them and relevant demographic, clinical and imaging variables were collected to evaluate its association and clinical expression, as well as the therapeutic approach after the findings.

RESULTS

The incidence of pneumatosis intestinalis after lung transplantation in our center was 3.1% (17/546), developing between 9 and 1270 days after transplantation (mean, 198 days; median 68 days). Most of the patients were asymptomatic or with mild symptoms, without any major analytical alterations, and with a cystic and expansive radiological appearance. Pneumoperitoneum was associated in 70% of the patients (12/17). Conservative treatment was chosen in all cases. The mean time to resolution was 389 days.

CONCLUSION

Pneumatosis intestinalis in lung transplant patients is a rare complication of uncertain origin, which can appear for a very long period of time after transplantation. It has little clinical relevance and can be managed without other diagnostic or therapeutic interventions.

摘要

简介

肠气肿是一种影像学表现,其特征为肠壁内存在气体,与多种实体相关。我们旨在了解其在肺移植患者中的发生率、病理生理学及其临床意义。

方法

在我院肺移植科的数据库中对肠气肿患者进行了检索。在所有患者中均证实了移植后存在肠气肿,并收集了相关的人口统计学、临床和影像学变量,以评估其相关性和临床表现,以及在发现后治疗方法。

结果

本中心肺移植后肠气肿的发生率为 3.1%(17/546),发生在移植后 9 至 1270 天(平均 198 天;中位数 68 天)。大多数患者无症状或症状轻微,无明显分析改变,影像学表现为囊性和扩展性。70%的患者(12/17)合并气腹。所有患者均选择保守治疗。平均缓解时间为 389 天。

结论

肺移植患者的肠气肿是一种起源不明的罕见并发症,在移植后很长一段时间内都可能出现。它的临床相关性较小,可以在不进行其他诊断或治疗干预的情况下进行管理。

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