Department of Neurosurgery, Beijing Jishuitan Hospital, Capital Medical University, No. 31, Xinjiekou East Street, Xicheng District, Beijing, 100035, China.
BMC Musculoskelet Disord. 2024 Aug 1;25(1):613. doi: 10.1186/s12891-024-07741-2.
Spinal intradural tumors are rare and heterogeneous in histological type, aggressiveness, and symptomatology, and there is a lack of data about them. This study investigated the epidemiological features of spinal intradural tumors.
This retrospective analysis included patients with spinal intradural tumors who underwent surgical treatment at the Myelopathy and Spondylosis Ward Beijing Jishuitan Hospital between January 2012 and December 2022.
This study included 1321 patients [aged 47.19 ± 14.90 years, 603 (45.65%) males] with spinal intradural tumors. The most common histological subtype was schwannoma [n = 511 (38.68%)], followed by spinal meningioma [n = 184 (13.93%)] and ependymoma [n = 101 (7.65%)]. Fifteen (1.14%) patients were diagnosed with metastatic spinal intradural tumors as a presentation of another primary cancer type. The spinal intradural tumors were mostly found in the lumbar region [n = 436 (33.01%)], followed by the thoracic vertebrae [n = 390 (29.52%)], cervical vertebrae [n = 154 (11.66%)], and thoracolumbar region [n = 111 (8.40%)]. Schwannomas mostly affected the lumbar region [n = 256 (52.64%)], spinal meningiomas in the thoracic region [n = 153 (83.15)], and ependymomas in the lumbar region [56 (55.45%)]. The de novo metastases were mostly found in the lumbar region [n = 8 (53.33%)].
According to the results of our single-center study, the most common spinal intradural tumor in Northern China is schwannoma, followed by spinal meningioma and ependymoma.
椎管内肿瘤在组织学类型、侵袭性和症状学方面均具有罕见且异质性的特点，且相关数据较为缺乏。本研究旨在探讨椎管内肿瘤的流行病学特征。
本回顾性分析纳入了 2012 年 1 月至 2022 年 12 月在北京积水潭医院脊髓病与脊柱外科病房接受手术治疗的椎管内肿瘤患者。
本研究共纳入 1321 例椎管内肿瘤患者[年龄 47.19±14.90 岁，男性 603 例（45.65%）]。最常见的组织学亚型是神经鞘瘤[511 例（38.68%）]，其次是脊髓脑膜瘤[184 例（13.93%）]和室管膜瘤[101 例（7.65%）]。15 例（1.14%）患者以椎管内转移瘤为首发表现，继发于其他原发性肿瘤类型。椎管内肿瘤主要发生在腰椎[436 例（33.01%）]，其次是胸椎[390 例（29.52%）]、颈椎[154 例（11.66%）]和胸腰椎[111 例（8.40%）]。神经鞘瘤主要影响腰椎[256 例（52.64%）]，脊髓脑膜瘤主要影响胸椎[153 例（83.15%）]，室管膜瘤主要影响腰椎[56 例（55.45%）]。新发生的转移瘤主要发生在腰椎[8 例（53.33%）]。
根据本单中心研究结果，中国北方最常见的椎管内肿瘤是神经鞘瘤，其次是脊髓脑膜瘤和室管膜瘤。
