Duke Clinical & Translational Science Institute, Duke University, Durham, North Carolina, USA.
Duke University School of Nursing, Durham, North Carolina, USA.
Clin Transl Sci. 2024 Aug;17(8):e13885. doi: 10.1111/cts.13885.
Prior research highlights that rural populations have been historically underrepresented/excluded from clinical research. The primary objective of this study was to describe the inclusion of rural populations within our research enterprise using Clinical Research Management System demographic information at a large academic medical center in the Southeast. This was a cross-sectional study using participant demographic information for all protocols entered into our Clinical Research Management System between May 2018 and March 2021. Descriptive statistics were used to analyze the representation of rural and non-rural participants and demographic breakdown by age, sex, race, and ethnicity for our entire enterprise and at the state level. We also compared Material Community Deprivation Index levels between urban and rural participants. Results indicated that 19% of the research population was classified as rural and 81% as non-rural for our entire sample, and 17.5% rural and 82.5% urban for our state-level sample. There were significant differences in race, sex, and age between rural and non-rural participants and Material Community Deprivation Indices between rural and non-rural participants. Lessons learned and recommendations for increasing the inclusion of rural populations in research are discussed.
先前的研究强调，农村人口在历史上一直被排除在临床研究之外。本研究的主要目的是使用东南某大型学术医疗中心的临床研究管理系统人口统计学信息，描述我们的研究机构中农村人口的纳入情况。这是一项横断面研究，使用了 2018 年 5 月至 2021 年 3 月期间所有纳入临床研究管理系统的方案的参与者人口统计学信息。描述性统计用于分析我们整个机构和州一级农村和非农村参与者的代表性以及年龄、性别、种族和民族的人口统计学细分。我们还比较了城乡参与者的物质社区贫困指数水平。结果表明，我们的整个样本中 19%的研究人群被归类为农村，81%为非农村，州一级样本中 17.5%为农村，82.5%为城市。农村和非农村参与者在种族、性别和年龄方面存在显著差异，农村和非农村参与者在物质社区贫困指数方面也存在显著差异。讨论了增加农村人口参与研究的经验教训和建议。
