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[接受系统对照访视的糖尿病患者糖化血红蛋白A1c与果糖胺检测之间的相关性。参考值的确定]

[Correlation between the assay of glycosylated hemoglobin A1c and fructosamine in diabetic patients submitted to a systematic control visit. Establishment of reference values].

作者信息

Sagniez M, Krempf M, Le Bastard N

出版信息

Pathol Biol (Paris). 1985 Nov;33(9):914-6.

PMID:3909084
Abstract

The plasmatic glycosyl proteins levels were measured in fifty non diabetic volunteers and thirty five patients with diabetes mellitus by the fructosamine test. The upper limit for healthy volunteers was estimated to 25 mumoles/g protein. A higher fructosamine concentration and greater spread of values were observed in the diabetic group. A very good correlation was noted in the diabetic group between A1C hemoglobin and fructosamine concentrations. This test is very reproducible, inexpensive and should be a good alternative to the A1C hemoglobin determination in some physiologic or pathologic disorders.

摘要

通过果糖胺试验对50名非糖尿病志愿者和35名糖尿病患者的血浆糖基化蛋白水平进行了测量。健康志愿者的上限估计为25微摩尔/克蛋白质。糖尿病组观察到更高的果糖胺浓度和更大的值范围。糖尿病组中糖化血红蛋白与果糖胺浓度之间存在非常好的相关性。该试验具有很高的重复性、成本低,在某些生理或病理疾病中应该是糖化血红蛋白测定的一个很好的替代方法。

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