Sindrup S H, Matzen L E, Wengler K, Frøland A, Reinholdt B
Nord Med. 1989;104(2):50-1, 53.
Fructosamine and various measures of blood glucose were compared to glycosylated hemoglobin as indices of glycaemic control in 148 patients with insulin treated diabetes. Fructosamine correlated fairly well with glycosylated hemoglobin (r = 0.67), but around 40 per cent of the patients with glycosylated hemoglobin below upper reference limit had a fructosamine value over upper reference limit and vice versa. The possibility to predict the level of glycosylated hemoglobin from fasting blood glucose, postprandial blood glucose, and self-measured blood glucose was poor. The difference in self-measured blood glucose from patients with high versus low levels of glycosylated hemoglobin was very modest (0.5-2.0 mmol/l). It is concluded that it is reasonable to measure both glycosylated hemoglobin and fructosamine to evaluate glycaemic control in insulin treated diabetic patients. Fasting blood glucose, postprandial blood glucose, and self-measured blood glucose only seem to reflect glycaemic control to a minor degree.
在148例接受胰岛素治疗的糖尿病患者中，比较了果糖胺和各种血糖指标与糖化血红蛋白作为血糖控制指标的情况。果糖胺与糖化血红蛋白的相关性较好（r = 0.67），但约40%糖化血红蛋白低于参考上限的患者果糖胺值高于参考上限，反之亦然。根据空腹血糖、餐后血糖和自我测量血糖来预测糖化血红蛋白水平的可能性较差。糖化血红蛋白水平高与低的患者自我测量血糖的差异非常小（0.5 - 2.0 mmol/L）。结论是，测量糖化血红蛋白和果糖胺以评估胰岛素治疗的糖尿病患者的血糖控制是合理的。空腹血糖、餐后血糖和自我测量血糖似乎仅在较小程度上反映血糖控制情况。
