Suppr超能文献

短暂性完全弱精子症

Transient Complete Asthenozoospermia.

作者信息

Kulla Artenisa, Mirza Basil, Campbell Kevin James

机构信息

College of Medicine, University of Florida, Gainesville, FL, USA.

Department of Urology, College of Medicine, University of Florida, Gainesville, FL, USA.

出版信息

J Hum Reprod Sci. 2024 Apr-Jun;17(2):133-135. doi: 10.4103/jhrs.jhrs_28_24. Epub 2024 May 28.

Abstract

Limited research exists on the mechanisms underlying asthenozoospermia associated with acquired ciliary dyskinesia. Primary ciliary dyskinesia links respiratory pathology with infertility and provides a basis for a potential mechanism. The aetiology of asthenozoospermia is often unclear and may be secondary to direct or indirect effects on sperm motility. Here, we report a case - with a brief clinical review - of recovering sperm motility after diagnosis of complete asthenozoospermia coinciding with resolution of chronic respiratory infections. The patient is a 36-year-old male, with initial semen analysis demonstrating 100% immotile sperm. Following the resolution of chronic respiratory infection, subsequent analysis demonstrated functional improvement with 76 million sperm/mL, 8% progressive motility and 4% strict morphology. Our case reinforces a potentially underappreciated role of environmental risk factors in infertility, with a focus on the patient's history of infections and other risk factors for acquired ciliary dyskinesia, which should be kept in mind when treating patients with asthenozoospermia.

摘要

关于与获得性纤毛运动障碍相关的弱精子症的潜在机制,现有研究有限。原发性纤毛运动障碍将呼吸道病理与不孕症联系起来,并为潜在机制提供了依据。弱精子症的病因往往不明,可能是对精子活力直接或间接影响的结果。在此,我们报告一例病例——并进行简要临床回顾——在诊断为完全性弱精子症且慢性呼吸道感染得到缓解后,精子活力恢复。患者为一名36岁男性,初始精液分析显示精子100%不活动。慢性呼吸道感染缓解后,后续分析显示功能改善,精子浓度为7600万/mL,进行性运动精子比例为8%,严格形态精子比例为4%。我们的病例强化了环境危险因素在不孕症中可能未得到充分重视的作用,重点关注患者的感染史和获得性纤毛运动障碍的其他危险因素,在治疗弱精子症患者时应牢记这些因素。

相似文献

1
Transient Complete Asthenozoospermia.
J Hum Reprod Sci. 2024 Apr-Jun;17(2):133-135. doi: 10.4103/jhrs.jhrs_28_24. Epub 2024 May 28.
3
A novel CCDC39 mutation causes multiple morphological abnormalities of the flagella in a primary ciliary dyskinesia patient.
Reprod Biomed Online. 2021 Nov;43(5):920-930. doi: 10.1016/j.rbmo.2021.07.005. Epub 2021 Jul 22.
8
Photobiomodulation with light-emitting diodes improves sperm motility in men with asthenozoospermia.
Lasers Med Sci. 2015 Jan;30(1):235-40. doi: 10.1007/s10103-014-1653-x. Epub 2014 Sep 10.
9
The sodium/proton exchanger SLC9C1 (sNHE) is essential for human sperm motility and fertility.
Clin Genet. 2021 May;99(5):684-693. doi: 10.1111/cge.13927. Epub 2021 Jan 25.
10
A novel mutation in PCD-associated gene DNAAF3 causes male infertility due to asthenozoospermia.
J Cell Mol Med. 2023 Oct;27(20):3107-3116. doi: 10.1111/jcmm.17881. Epub 2023 Aug 3.

本文引用的文献

1
Male infertility.
Nat Rev Dis Primers. 2023 Sep 14;9(1):49. doi: 10.1038/s41572-023-00459-w.
2
A Case of Asthenozoospermia Following COVID-19 Infection.
Reprod Sci. 2022 Sep;29(9):2703-2705. doi: 10.1007/s43032-022-00975-2. Epub 2022 May 23.
3
ICSI outcomes for infertile men with severe or complete asthenozoospermia.
Basic Clin Androl. 2022 Apr 5;32(1):6. doi: 10.1186/s12610-022-00155-x.
4
Role of oxidative stress, infection and inflammation in male infertility.
Andrologia. 2018 Dec;50(11):e13126. doi: 10.1111/and.13126.
5
Sperm of patients with severe asthenozoospermia show biochemical, molecular and genomic alterations.
Reproduction. 2016 Dec;152(6):695-704. doi: 10.1530/REP-16-0342. Epub 2016 Sep 20.
6
Absolute asthenozoospermia and ICSI: what are the options?
Hum Reprod Update. 2011 Sep-Oct;17(5):684-92. doi: 10.1093/humupd/dmr018. Epub 2011 Aug 3.
7
World Health Organization reference values for human semen characteristics.
Hum Reprod Update. 2010 May-Jun;16(3):231-45. doi: 10.1093/humupd/dmp048. Epub 2009 Nov 24.
8
Secondary ciliary dyskinesia in upper respiratory tract.
Acta Otorhinolaryngol Belg. 2000;54(3):309-16.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验