Davies Nyle H, Lewis Julia, John Bev, Quelch Darren, Roderique-Davies Gareth
Addictions Research Group, Faculty of Life Science and Education, University of South Wales, Pontypridd, United Kingdom.
Aneurin Bevan Specialist Drug and Alcohol Service, Newport, United Kingdom.
Front Psychiatry. 2024 Jul 17;15:1377039. doi: 10.3389/fpsyt.2024.1377039. eCollection 2024.
Alcohol dependence is a global issue with many negative consequences, including alcohol-related brain damage (ARBD). Assessment of the sociodemographic and cognitive characteristics of individuals with confirmed or suspected ARBD presenting to alcohol services warrants further investigation.
This study retrospectively examined rates of cognitive impairment using Montreal Cognitive Assessment (MoCA) data from 300 adults who visited three alcohol support services. We demonstrate that 55.3% of the sample had significant levels of cognitive impairment. Females' cognitive performance was disproportionately negatively affected by historical alcohol use relative to males.
The analysis identified four categories of participants, and the majority had a long history (+10 years) of alcohol use and were still actively drinking. Those taking part in active treatment for ARBD or practising abstinence demonstrated lower levels of cognitive impairment. Additionally, prior access to specialised ARBD care was associated with higher MoCA scores.
This research has identified a range of key service engagement, sociodemographic and cognitive characteristics that could be used to optimise support for those with alcohol dependence, whilst also highlighting some critical questions to be addressed in future research.
酒精依赖是一个全球性问题,会带来许多负面后果,包括酒精相关脑损伤(ARBD)。对前来酒精服务机构就诊的确诊或疑似患有ARBD的个体的社会人口学和认知特征进行评估,值得进一步研究。
本研究回顾性地使用来自300名前往三个酒精支持服务机构就诊的成年人的蒙特利尔认知评估(MoCA)数据,对认知障碍发生率进行了研究。我们发现,55.3%的样本存在显著程度的认知障碍。相对于男性,女性的认知表现受既往饮酒史的负面影响更为严重。
分析确定了四类参与者,其中大多数有较长(超过10年)的饮酒史且仍在积极饮酒。接受ARBD积极治疗或戒酒的参与者认知障碍水平较低。此外,先前获得专门的ARBD护理与较高的MoCA分数相关。
本研究确定了一系列关键的服务参与度、社会人口学和认知特征,这些特征可用于优化对酒精依赖者的支持,同时也突出了未来研究中需要解决的一些关键问题。