[辐照大鼠胸腺细胞中核基质结构变化的免疫化学分析]
[Immunochemical analysis of changes in the structure of the nuclear matrix in thymocytes of irradiated rats].
作者信息
Nazarova L F, Zotova R N, Ermekova V M, Umanskiĭ S R
出版信息
Radiobiologiia. 1985 Nov-Dec;25(6):778-81.
PMID:3909212
Abstract
It was shown that reactivity of the nuclear matrix of thymocytes for antibodies against chromatin of the control and irradiated thymocytes and PDN did not change immediately and increased markedly 2 h following irradiation of rats with a dose of 10 Gy. The method of immunoblotting failed to reveal any qualitative differences in the protein content of the thymocyte nuclear matrix of the control and exposed rats.
摘要
结果表明，胸腺细胞核基质对针对对照及照射后胸腺细胞和PDN染色质的抗体的反应性并未立即改变，而是在给大鼠10 Gy剂量照射后2小时显著增加。免疫印迹法未能揭示对照大鼠和受照射大鼠胸腺细胞核基质蛋白质含量的任何定性差异。
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