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细菌性气管炎:一种常见疾病的新表现形式。

Bacterial Tracheitis: A New Presentation of a Well-Known Disease.

作者信息

Moreira Mafalda, Ferreira Paula Regina, Sarmento Alzira, Cardoso Ana Lúcia

机构信息

Pediatrics and Child Health, Centro Hospitalar do Tâmega e Sousa, Penafiel, PRT.

Pediatric Intensive Care Unit, Centro Materno Infantil do Norte, Centro Hospitalar Universitário de Santo António, Porto, PRT.

出版信息

Cureus. 2024 Jul 2;16(7):e63697. doi: 10.7759/cureus.63697. eCollection 2024 Jul.

DOI:10.7759/cureus.63697
PMID:39092363
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11293875/
Abstract

Bacterial tracheitis (BT) is an uncommon life-threatening condition that results in acute upper airway obstruction. Classical signs include a toxic appearance, stridor, tachypnoea, and fever, often leading to rapid clinical deterioration. Recent studies have shown a shift in BT epidemiology and presentation, where stridor and respiratory distress are now predominant. A poor response to corticosteroids or nebulized epinephrine is also commonly described, along with a need for mechanical ventilation. We present the case of a five-year-old boy admitted to the emergency department with cough, stridor, and dyspnea that had significantly worsened over the previous hours. He presented reasonable general condition, marked retractions, poor air entry, stridor, and wheezing. Investigation revealed a slight elevation of C-reactive protein and leukocytosis with neutrophilia. Anteroposterior x-ray showed narrowing of subglottic airways (steeple sign). There was no response to oral/nebulized corticoids, nebulized adrenaline, or bag-valve-mask oxygenation. Antibiotic therapy with ceftriaxone was initiated. Due to deteriorating clinical conditions with severe respiratory acidosis, orotracheal intubation was required. Later was isolated in the bronchial secretions and a targeted antibiotic regimen was administered. Progressive clinical and analytical improvement was observed with no complications. Although uncommon, BT remains a severe infectious condition affecting otherwise healthy children. Our case underscores the severity of the disease and the imperative for invasive interventions to achieve favorable outcomes. It also supports recent findings indicating a shift in predominant symptoms and prognosis. Clinicians must be vigilant and knowledgeable, recognizing that worsening stridor and respiratory distress unresponsive to conservative treatment are key indicators for diagnosing BT.

摘要

细菌性气管支气管炎(BT)是一种罕见但危及生命的疾病,可导致急性上呼吸道梗阻。典型症状包括中毒面容、喘鸣、呼吸急促和发热,常导致临床迅速恶化。最近的研究表明,BT的流行病学和临床表现发生了变化,现在喘鸣和呼吸窘迫更为常见。通常还会描述对皮质类固醇或雾化肾上腺素反应不佳,以及需要机械通气。我们报告一例5岁男孩因咳嗽、喘鸣和呼吸困难入院急诊,这些症状在过去几个小时内明显加重。他的一般状况尚可,有明显的吸气凹陷、呼吸音减弱、喘鸣和哮鸣音。检查发现C反应蛋白略有升高,白细胞增多伴中性粒细胞增多。前后位X线片显示声门下气道狭窄(尖塔征)。口服/雾化皮质类固醇、雾化肾上腺素或袋阀面罩给氧均无反应。开始使用头孢曲松进行抗生素治疗。由于临床状况恶化并伴有严重呼吸性酸中毒,需要进行经口气管插管。后来在支气管分泌物中分离出[病原体名称未给出],并给予针对性的抗生素治疗方案。观察到临床和分析指标逐渐改善,无并发症发生。尽管BT不常见,但它仍然是一种严重的感染性疾病,会影响原本健康的儿童。我们的病例强调了该疾病的严重性以及进行侵入性干预以获得良好预后的必要性。它也支持了最近关于主要症状和预后发生变化的研究结果。临床医生必须保持警惕并具备相关知识,认识到喘鸣和呼吸窘迫加重且对保守治疗无反应是诊断BT的关键指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d591/11293875/325d85232bb5/cureus-0016-00000063697-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d591/11293875/325d85232bb5/cureus-0016-00000063697-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d591/11293875/325d85232bb5/cureus-0016-00000063697-i01.jpg

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[Bacterial tracheitis: an infectious cause of upper airway obstruction to be considered in children].[细菌性气管炎:一种在儿童中需考虑的上气道梗阻的感染性病因]
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