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[从软体动物中制备类胰岛素物质及其抗血清]

[Preparation of an insulin-like substance from molluscs and its antiserum].

作者信息

Rusakov Iu I, Kazakov V K

出版信息

Zh Evol Biokhim Fiziol. 1979 Nov-Dec;15(6):617-9.

PMID:390928
Abstract

A substance with insulin-like activity was obtained from visceral organs (excluding foot, gills and mantle) of the freshwater bivalve molluscs Unio pictorum and Anodonta cygnea. Injecting this substance to guinea pigs, antiserum was also obtained. Using the obtained antiserum in immunostaining experiments, the cells which produce insulin-like substance were identified in the intestinal epithelium of the midgut in A. cygnea.

摘要

从淡水双壳贝类软体动物绘环棱螺和天鹅河蚌的内脏器官(不包括足部、鳃和外套膜)中获得了一种具有胰岛素样活性的物质。将该物质注射到豚鼠体内,也获得了抗血清。在免疫染色实验中使用所获得的抗血清,在天鹅河蚌中肠的肠上皮中鉴定出了产生胰岛素样物质的细胞。

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