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[从软体动物中制备类胰岛素物质及其抗血清]

[Preparation of an insulin-like substance from molluscs and its antiserum].

作者信息

Rusakov Iu I, Kazakov V K

出版信息

Zh Evol Biokhim Fiziol. 1979 Nov-Dec;15(6):617-9.

PMID:390928
Abstract

A substance with insulin-like activity was obtained from visceral organs (excluding foot, gills and mantle) of the freshwater bivalve molluscs Unio pictorum and Anodonta cygnea. Injecting this substance to guinea pigs, antiserum was also obtained. Using the obtained antiserum in immunostaining experiments, the cells which produce insulin-like substance were identified in the intestinal epithelium of the midgut in A. cygnea.

摘要

从淡水双壳贝类软体动物绘环棱螺和天鹅河蚌的内脏器官(不包括足部、鳃和外套膜)中获得了一种具有胰岛素样活性的物质。将该物质注射到豚鼠体内,也获得了抗血清。在免疫染色实验中使用所获得的抗血清,在天鹅河蚌中肠的肠上皮中鉴定出了产生胰岛素样物质的细胞。

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1
[Preparation of an insulin-like substance from molluscs and its antiserum].[从软体动物中制备类胰岛素物质及其抗血清]
Zh Evol Biokhim Fiziol. 1979 Nov-Dec;15(6):617-9.
2
[Insulin in mollusks and its role in regulating carbohydrate metabolism].[软体动物中的胰岛素及其在调节碳水化合物代谢中的作用]
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Insulin-producing cells in the gut of freshwater bivalve molluscs Anodonta cygnea and Unio pictorum and the role of insulin in the regulation of their carbohydrate metabolism.
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[Certain biochemical characteristics of an insulin-like substance from the bivalve mollusk Anodonta cygnea].[来自双壳贝类河蚌的一种胰岛素样物质的某些生化特性]
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[Insulin-like peptides of cerebro-pleural ganglia of the mollusc Anodonta cygnea: isolation, purification and radioligand analysis].
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Protection against autoimmune thyroiditis in guinea pigs by thyroglobulin antiserum.甲状腺球蛋白抗血清对豚鼠自身免疫性甲状腺炎的保护作用。
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