Department of Radiology, Izmir Bakircay University Cigli Training and Research Hospital, İzmir-Türkiye.
Department of Internal Medicine Division of Hematology, Izmir Bakircay University Faculty of Medicine, Cigli Hospital, İzmir-Türkiye.
Ulus Travma Acil Cerrahi Derg. 2024 Aug;30(8):531-536. doi: 10.14744/tjtes.2024.31531.
This study explored the potential of non-contrast thoracic computed tomography (CT) to predict anemia by correlating CT parameters with hemoglobin (Hb) levels in patients who underwent non-contrast thoracic CT for various indications.
This retrospective study included 150 patients who underwent non-contrast thoracic CT scans and complete blood counts within 24 hours at our center between January and June 2023. Exclusion criteria included acute bleeding, iron accumulation disorders, recent transfusions, pregnancy, and certain thoracic CT artifacts. Hounsfield Unit (HU) measurements were obtained from the ascending aorta, left ventricular cavity, and descending aorta, and compared with Hb and hematocrit (Htc) values. Anemia indicators such as the 'Aortic Ring Sign (ARS)' and the 'Hyperdense Septum Sign (HSS)' were also evaluated.
Anemic patients (48%) exhibited significantly lower HU measurements at all three CT scan locations and higher instances of ARS and HSS compared to non-anemic patients. Notably, the presence of HSS and ARS was strongly associated with anemia. Thresholds for HU measurements corresponding to anemia were determined using receiver operating characteristic curve analysis, which also revealed strong positive correlations between HU measurements and Hb/Htc levels.
The study concludes that non-contrast thoracic CT parameters, particularly HU measurements and the presence of ARS and HSS, are significantly associated with anemia. These CT indicators could serve as reliable, non-invasive markers for predicting anemia in patients, potentially aiding in the early diagnosis and management of the condition.
本研究通过将 CT 参数与血红蛋白（Hb）水平相关联，探索非增强性胸部 CT 预测贫血的潜力，这些患者因各种原因接受了非增强性胸部 CT 检查。
这是一项回顾性研究，共纳入了 2023 年 1 月至 6 月期间在我们中心接受非增强性胸部 CT 扫描和 24 小时内全血细胞计数的 150 例患者。排除标准包括急性出血、铁蓄积障碍、近期输血、妊娠和某些胸部 CT 伪影。从升主动脉、左心室腔和降主动脉获得亨氏单位（HU）测量值，并与 Hb 和红细胞压积（Htc）值进行比较。还评估了贫血指标，如“主动脉环征（ARS）”和“高密度隔征（HSS）”。
贫血患者（48%）在所有三个 CT 扫描位置的 HU 测量值显著较低，且 ARS 和 HSS 的发生率较高，与非贫血患者相比。值得注意的是，HSS 和 ARS 的存在与贫血密切相关。使用受试者工作特征曲线分析确定 HU 测量值对应贫血的阈值，该分析还显示 HU 测量值与 Hb/Htc 水平之间存在强烈的正相关关系。
本研究得出结论，非增强性胸部 CT 参数，特别是 HU 测量值以及 ARS 和 HSS 的存在，与贫血显著相关。这些 CT 指标可作为预测患者贫血的可靠、非侵入性标志物，可能有助于贫血的早期诊断和管理。
