Department of Radiology, Graduate School of Medical Sciences, The University of Tokushima, Tokushima, Japan.
Jpn J Radiol. 2010 Jan;28(1):53-7. doi: 10.1007/s11604-009-0385-5. Epub 2010 Jan 30.
The purpose of this study was to determine which computed tomography (CT) attenuation parameter was the most appropriate to predict the presence or severity of anemia.
The subjects of the study wer 500 patients who had undergone a peripheral blood examination within 24 h of an unenhanced CT scan. Regions of interest were placed in the left ventricular (LV) cavity, thoracic and abdominal aortic lumens, inferior vena cava, and interventricular septum. The CT attenuation difference between the LV cavity and interventricular septum was also calculated. The relation between these measurements and the blood hemoglobin level was analyzed. In addition, using several selected parameters, a receiver operating characteristic (ROC) analysis was also performed.
The difference in CT attenuation between the LV cavity and interventricular septum revealed the greatest correlation. ROC analyses also revealed the greatest area under the ROC curve in the differences between CT attenuation.
The best quantitative method for the diagnosis of anemia was the difference in CT attenuation between the left ventricle and interventricular septum.
本研究旨在确定哪种计算机断层扫描（CT）衰减参数最适合预测贫血的存在或严重程度。
本研究的对象为 500 名患者，他们在未增强 CT 扫描后 24 小时内进行了外周血检查。在左心室（LV）腔、胸主动脉和腹主动脉管腔、下腔静脉和室间隔中放置感兴趣区。还计算了 LV 腔和室间隔之间的 CT 衰减差异。分析了这些测量值与血液血红蛋白水平之间的关系。此外，还使用了几个选定的参数进行了受试者工作特征（ROC）分析。
LV 腔和室间隔之间的 CT 衰减差异显示出最大的相关性。ROC 分析还显示 CT 衰减差异的 ROC 曲线下面积最大。
诊断贫血的最佳定量方法是左心室和室间隔之间的 CT 衰减差异。
