Department of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.
Expert Rev Gastroenterol Hepatol. 2024 Jul;18(7):315-323. doi: 10.1080/17474124.2024.2388797. Epub 2024 Aug 5.
Symptomatic uncomplicated diverticular disease (SUDD) is a clinical condition included in the spectrum of symptomatic diverticular disease. The symptom profile associated with SUDD is highly heterogeneous, as there are currently discordant definitions, that encompass many clinical scenarios.
We conducted a narrative review to assess the symptom profile and diagnostic criteria of SUDD based on the available evidence. A thorough literature search was performed on PubMed following the SANRA scale. Abdominal pain, regardless of its duration and location, emerges as the cardinal symptom of SUDD, suggesting that it should be central to its diagnosis. Although abdominal bloating and changes in bowel habits are commonly reported, they do not appear to be specifically attributable to SUDD. Other issues considered are the possible overlap with irritable bowel syndrome and the identification of a subcategory of SUDD patients with chronic symptoms following an episode of acute diverticulitis.
The future agenda should include the development of shared diagnostic criteria for SUDD, including well-defined inclusion and exclusion clinical features and symptom patterns.
有症状的单纯性憩室病(SUDD)是一种包含在有症状憩室病谱中的临床情况。与 SUDD 相关的症状谱具有高度异质性,因为目前存在不一致的定义,涵盖了许多临床情况。
我们根据现有证据进行了叙述性综述,以评估 SUDD 的症状谱和诊断标准。按照 SANRA 标准,我们在 PubMed 上进行了全面的文献检索。腹痛是 SUDD 的主要症状,无论其持续时间和位置如何,这表明它应该是其诊断的核心。尽管腹部胀气和排便习惯的改变是常见的,但它们似乎并不是 SUDD 特有的。其他需要考虑的问题是与肠易激综合征的可能重叠,以及在急性憩室炎发作后,确定具有慢性症状的 SUDD 患者亚类。
未来的议程应包括为 SUDD 制定共同的诊断标准,包括明确的纳入和排除临床特征和症状模式。