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基于单中心结肠镜的队列研究:有症状但无并发症的憩室病的流行率可能低于预期。

The prevalence of symptomatic uncomplicated diverticular disease could be lower than expected: a single-center colonoscopy-based cohort study.

机构信息

Territorial Gastroenterology Service, ASL BAT, Andria (BT).

Department of Medical and Surgical Sciences, Post-graduate School of Digestive Diseases, Catholic University.

出版信息

Eur J Gastroenterol Hepatol. 2021 Dec 1;33(1S Suppl 1):e478-e483. doi: 10.1097/MEG.0000000000002142.

Abstract

AIM

The real prevalence of symptomatic uncomplicated diverticular disease (SUDD) is still unknown. The aim of this study was to assess the prevalence of SUDD, post-diverticulitis SUDD (PD-SUDD) and irritable bowel syndrome (IBS)-like symptoms in a real-life population.

METHODS

A cohort of patients, submitted to colonoscopy from 1st January 2012 to 30th April 2018 was revised.

RESULTS

A cohort of 5451 patients with diverticulosis was identified during the study period. Abdominal pain was recorded in 1141 patients (20.93%), diarrhea in 288 (5.28%) and constipation in 536 (9.83%) patients. SUDD was recorded in 371 patients (6.81% of the patients having diverticulosis and 32.51% of the patients experiencing abdominal pain), PD-SUDD was recorded in 103 patients (1.89% of the patients having diverticulosis and 9.03% of the patients experiencing abdominal pain) and IBS-like was recorded in 348 patients (6.38% of the patients having diverticulosis and 30.5% of the patients experiencing abdominal pain). Three hundred and nineteen patients were not part of any of the previous categories (5.85% of the patients having diverticulosis and 27.96% of the patients experiencing abdominal pain). SUDD and PD-SUDD were more frequent in older ages (>60 years), while IBS-like symptoms were more frequent in younger. Nonspecific abdominal pain was equally distributed in through the ages.

CONCLUSION

The prevalence of SUDD seems to be lower than expected, and most of patients with diverticulosis and abdominal symptoms may suffer from IBS-like or other causes.

摘要

目的

症状性单纯性憩室病(SUDD)的真实患病率仍不清楚。本研究旨在评估真实人群中 SUDD、憩室炎后 SUDD(PD-SUDD)和肠易激综合征(IBS)样症状的患病率。

方法

对 2012 年 1 月 1 日至 2018 年 4 月 30 日接受结肠镜检查的患者队列进行了回顾。

结果

在研究期间,共确定了 5451 例憩室病患者。1141 例(20.93%)患者记录有腹痛,288 例(5.28%)患者有腹泻,536 例(9.83%)患者有便秘。371 例(6.81%的憩室病患者和 32.51%的腹痛患者)患有 SUDD,103 例(6.81%的憩室病患者和 9.03%的腹痛患者)患有 PD-SUDD,348 例(6.38%的憩室病患者和 30.5%的腹痛患者)患有 IBS 样症状。319 例患者不属于上述任何一种类别(6.81%的憩室病患者和 27.96%的腹痛患者)。SUDD 和 PD-SUDD 在年龄较大(>60 岁)的患者中更为常见,而 IBS 样症状在年龄较小的患者中更为常见。非特异性腹痛在各年龄段分布均匀。

结论

SUDD 的患病率似乎低于预期,大多数患有憩室病和腹部症状的患者可能患有 IBS 样或其他原因。

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