Cavanaugh Priscilla K, Dragisic Marko V, Peck Kathryn, Kaplan F Thomas D, Merrell Gregory
Indiana Hand to Shoulder Center, Indianapolis, IN.
Indiana Hand to Shoulder Center, Indianapolis, IN.
J Hand Surg Am. 2025 May;50(5):581-586. doi: 10.1016/j.jhsa.2024.05.016. Epub 2024 Aug 1.
This study aimed to report pain during and following injection for trigger finger as well as failure to resolve triggering. We hypothesized that a corticosteroid injection alone would be equally or less painful compared with the standard combination of corticosteroid and lidocaine for the treatment of trigger fingers, and there would be no difference in the resolution of triggering.
Our study was a prospective, single-blinded, randomized controlled trial at a single institution, comprising 76 patients with a diagnosis of trigger finger. Each treatment group consisted of 38 patients. Patients were randomized to receive either a betamethasone (1 mL, 6 mg) injection without lidocaine or a betamethasone injection (1 mL, 6 mg) with 1% lidocaine (1 mL). Patients were assessed during injection and at 1 hour, 6 hours, 2 days, and 6 weeks after the injection. The primary outcome was pain measured using a numerical rating scale. The secondary outcome was the rate of failure to resolve symptoms at 6 weeks.
There was a statistically significant difference in pain scores between the lidocaine and betamethasone versus betamethasone-only injections during administration (4.6 vs 6.2) and after 1 hour (1.3 vs 2.5). There was no statistically significant difference in pain scores after 6 hours (1.5 vs 2.0) and 2 days (0.7 vs 0.6) or in failure rate at the 6-week time point (21% vs 18%).
This study showed that there is a statistically significant difference in pain during and shortly after injection when using a steroid with lidocaine versus steroid alone for the treatment of trigger finger, but that difference may not be clinically relevant. There was no significant difference in the failure rate between the treatments.
TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic II.
本研究旨在报告扳机指注射期间及注射后的疼痛情况以及扳机症状未缓解的情况。我们假设,对于扳机指的治疗,单纯皮质类固醇注射与皮质类固醇和利多卡因的标准联合注射相比,疼痛程度相同或更低,且在扳机症状的缓解方面无差异。
我们的研究是在单一机构进行的一项前瞻性、单盲、随机对照试验,纳入76例诊断为扳机指的患者。每个治疗组由38例患者组成。患者被随机分为两组,一组接受不含利多卡因的倍他米松(1 mL,6 mg)注射,另一组接受含1%利多卡因(1 mL)的倍他米松注射(1 mL,6 mg)。在注射期间以及注射后1小时、6小时、2天和6周对患者进行评估。主要结局指标是使用数字评分量表测量的疼痛程度。次要结局指标是6周时症状未缓解的发生率。
在注射期间(4.6对6.2)和1小时后(1.3对2.5),利多卡因和倍他米松联合注射组与单纯倍他米松注射组的疼痛评分存在统计学显著差异。6小时后(1.5对2.0)和2天后(0.7对0.6)的疼痛评分以及6周时间点的失败率(21%对18%)无统计学显著差异。
本研究表明,对于扳机指的治疗,使用类固醇加利多卡因与单纯使用类固醇相比,在注射期间及注射后不久的疼痛存在统计学显著差异,但该差异可能无临床意义。两种治疗方法在失败率方面无显著差异。
研究类型/证据水平:治疗性II级。