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[霍乱弧菌不完全L型阶段胆汁生成能力的保存]

[Preservation of cholerogenicity in cholera vibrios in the incomplete L-cycle stage].

作者信息

Emdina I A, Podosinnikova L S, Somova A G, Miliutin V N, Prozorovskiĭ S V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1979 Nov(11):82-6.

PMID:390934
Abstract

The work presents the characteristics of the forms appearing as a result of the incomplete L cycle of Vibrio cholerae obtained in experimental conditions after the cultivation of typical V. eltor strain, serovar Ogawa, for 5 months at room temperature in sterile river water without subculturing. The culture formed shaprly changed L-similar colonies, had decreased agglutinability and was resistant to diagnostic cholera phages, but retained its cholerogenicity for suckling rabbits. A suggestion was made concerning the possible epidemiological significance of such forms and the necessity of their detection in the course of bacteriological analysis for cholera.

摘要

该研究呈现了在实验条件下,将典型的埃尔托型霍乱弧菌小川血清型菌株于无菌河水中室温培养5个月且未传代后,因霍乱弧菌L型周期不完全而出现的菌体形态特征。该培养物形成了形态明显改变的类似L型的菌落,凝集性降低,对霍乱诊断噬菌体具有抗性,但对乳兔仍保留其产毒性。文中针对这些形态可能的流行病学意义以及在霍乱细菌学分析过程中检测它们的必要性提出了建议。

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